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The lysosomal Ragulator complex activates NLRP3 inflammasome in vivo via HDAC6.
Tsujimoto K, Jo T, Nagira D, Konaka H, Park JH, Yoshimura SI, Ninomiya A, Sugihara F, Hirayama T, Itotagawa E, Matsuzaki Y, Takaichi Y, Aoki W, Saita S, Nakamura S, Ballabio A, Nada S, Okada M, Takamatsu H, Kumanogoh A. Tsujimoto K, et al. Among authors: park jh. EMBO J. 2023 Jan 4;42(1):e111389. doi: 10.15252/embj.2022111389. Epub 2022 Nov 29. EMBO J. 2023. PMID: 36444797 Free PMC article.
Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis.
Nishide M, Nojima S, Ito D, Takamatsu H, Koyama S, Kang S, Kimura T, Morimoto K, Hosokawa T, Hayama Y, Kinehara Y, Kato Y, Nakatani T, Nakanishi Y, Tsuda T, Park JH, Hirano T, Shima Y, Narazaki M, Morii E, Kumanogoh A. Nishide M, et al. Among authors: park jh. Ann Rheum Dis. 2017 Aug;76(8):1440-1448. doi: 10.1136/annrheumdis-2016-210706. Epub 2017 Apr 17. Ann Rheum Dis. 2017. PMID: 28416516 Free PMC article.
A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling.
Briones JC, Espulgar WV, Koyama S, Yoshikawa H, Park J, Naito Y, Kumanogoh A, Tamiya E, Takamatsu H, Saito M. Briones JC, et al. Theranostics. 2020 Jan 1;10(1):123-132. doi: 10.7150/thno.37728. eCollection 2020. Theranostics. 2020. PMID: 31903110 Free PMC article.
SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced by glomeruli in lupus nephritis.
Itotagawa E, Tomofuji Y, Kato Y, Konaka H, Tsujimoto K, Park J, Nagira D, Hirayama T, Jo T, Hirano T, Morita T, Nishide M, Nishida S, Shima Y, Narazaki M, Okada Y, Takamatsu H, Kumanogoh A. Itotagawa E, et al. Rheumatology (Oxford). 2023 May 2;62(5):1988-1997. doi: 10.1093/rheumatology/keac528. Rheumatology (Oxford). 2023. PMID: 36094336 Free PMC article.
Secretion of mitochondrial DNA via exosomes promotes inflammation in Behçet's syndrome.
Konaka H, Kato Y, Hirano T, Tsujimoto K, Park J, Koba T, Aoki W, Matsuzaki Y, Taki M, Koyama S, Itotagawa E, Jo T, Hirayama T, Kawai T, Ishii KJ, Ueda M, Yamaguchi S, Akira S, Morita T, Maeda Y, Nishide M, Nishida S, Shima Y, Narazaki M, Takamatsu H, Kumanogoh A. Konaka H, et al. EMBO J. 2023 Oct 16;42(20):e112573. doi: 10.15252/embj.2022112573. Epub 2023 Sep 4. EMBO J. 2023. PMID: 37661814 Free PMC article.
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