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Page 1
mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome.
Huang Z, You X, Chen L, Du Y, Brodeur K, Jee H, Wang Q, Linder G, Darbousset R, Cunin P, Chang MH, Wactor A, Wauford BM, Todd MJC, Wei K, Li Y, Levescot A, Iwakura Y, Pascual V, Baldwin NE, Quartier P, Li T, Gianatasio MT, Hasserjian RP, Henderson LA, Sykes DB, Mellins ED, Canna SW, Charles JF, Nigrovic PA, Lee PY. Huang Z, et al. Among authors: baldwin ne. Nat Commun. 2022 Nov 28;13(1):6915. doi: 10.1038/s41467-022-34480-6. Nat Commun. 2022. PMID: 36443301 Free PMC article.
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.
Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, Frickel E, Sesay AK, Priestnall SL, Herbert E, Ioannou M, Wang Q, Humphreys IR, Dodd J, Openshaw PJM, Mayer-Barber KD, Jankovic D, Sher A, Lloyd CM, Baldwin N, Chaussabel D, Papayannopoulos V, Wack A, Banchereau JF, Pascual VM, O'Garra A. Singhania A, et al. Nat Commun. 2019 Jun 28;10(1):2887. doi: 10.1038/s41467-019-10601-6. Nat Commun. 2019. PMID: 31253760 Free PMC article.
Transcriptional specialization of human dendritic cell subsets in response to microbial vaccines.
Banchereau R, Baldwin N, Cepika AM, Athale S, Xue Y, Yu CI, Metang P, Cheruku A, Berthier I, Gayet I, Wang Y, Ohouo M, Snipes L, Xu H, Obermoser G, Blankenship D, Oh S, Ramilo O, Chaussabel D, Banchereau J, Palucka K, Pascual V. Banchereau R, et al. Nat Commun. 2014 Oct 22;5:5283. doi: 10.1038/ncomms6283. Nat Commun. 2014. PMID: 25335753 Free PMC article.
Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data.
Altman MC, Rinchai D, Baldwin N, Toufiq M, Whalen E, Garand M, Syed Ahamed Kabeer B, Alfaki M, Presnell SR, Khaenam P, Ayllón-Benítez A, Mougin F, Thébault P, Chiche L, Jourde-Chiche N, Phillips JT, Klintmalm G, O'Garra A, Berry M, Bloom C, Wilkinson RJ, Graham CM, Lipman M, Lertmemongkolchai G, Bedognetti D, Thiebaut R, Kheradmand F, Mejias A, Ramilo O, Palucka K, Pascual V, Banchereau J, Chaussabel D. Altman MC, et al. Nat Commun. 2021 Jul 19;12(1):4385. doi: 10.1038/s41467-021-24584-w. Nat Commun. 2021. PMID: 34282143 Free PMC article.
A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4.
Alsina L, Israelsson E, Altman MC, Dang KK, Ghandil P, Israel L, von Bernuth H, Baldwin N, Qin H, Jin Z, Banchereau R, Anguiano E, Ionan A, Abel L, Puel A, Picard C, Pascual V, Casanova JL, Chaussabel D. Alsina L, et al. Nat Immunol. 2014 Dec;15(12):1134-42. doi: 10.1038/ni.3028. Epub 2014 Oct 26. Nat Immunol. 2014. PMID: 25344726 Free PMC article.
IFN priming is necessary but not sufficient to turn on a migratory dendritic cell program in lupus monocytes.
Rodriguez-Pla A, Patel P, Maecker HT, Rossello-Urgell J, Baldwin N, Bennett L, Cantrell V, Baisch J, Punaro M, Gotte A, Nassi L, Wright T, Palucka AK, Banchereau J, Pascual V. Rodriguez-Pla A, et al. J Immunol. 2014 Jun 15;192(12):5586-98. doi: 10.4049/jimmunol.1301319. Epub 2014 May 14. J Immunol. 2014. PMID: 24829414 Free PMC article. Clinical Trial.
Molecular determinants of response to PD-L1 blockade across tumor types.
Banchereau R, Leng N, Zill O, Sokol E, Liu G, Pavlick D, Maund S, Liu LF, Kadel E 3rd, Baldwin N, Jhunjhunwala S, Nickles D, Assaf ZJ, Bower D, Patil N, McCleland M, Shames D, Molinero L, Huseni M, Sanjabi S, Cummings C, Mellman I, Mariathasan S, Hegde P, Powles T. Banchereau R, et al. Nat Commun. 2021 Jun 25;12(1):3969. doi: 10.1038/s41467-021-24112-w. Nat Commun. 2021. PMID: 34172722 Free PMC article. Clinical Trial.
A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis.
Cepika AM, Banchereau R, Segura E, Ohouo M, Cantarel B, Goller K, Cantrell V, Ruchaud E, Gatewood E, Nguyen P, Gu J, Anguiano E, Zurawski S, Baisch JM, Punaro M, Baldwin N, Obermoser G, Palucka K, Banchereau J, Amigorena S, Pascual V. Cepika AM, et al. J Exp Med. 2017 Nov 6;214(11):3449-3466. doi: 10.1084/jem.20170412. Epub 2017 Sep 21. J Exp Med. 2017. PMID: 28935693 Free PMC article.
Transcriptional fingerprints of antigen-presenting cell subsets in the human vaginal mucosa and skin reflect tissue-specific immune microenvironments.
Duluc D, Banchereau R, Gannevat J, Thompson-Snipes L, Blanck JP, Zurawski S, Zurawski G, Hong S, Rossello-Urgell J, Pascual V, Baldwin N, Stecher J, Carley M, Boreham M, Oh S. Duluc D, et al. Genome Med. 2014 Nov 25;6(11):98. doi: 10.1186/s13073-014-0098-y. eCollection 2014. Genome Med. 2014. PMID: 25520755 Free PMC article.
A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus.
Chaussabel D, Quinn C, Shen J, Patel P, Glaser C, Baldwin N, Stichweh D, Blankenship D, Li L, Munagala I, Bennett L, Allantaz F, Mejias A, Ardura M, Kaizer E, Monnet L, Allman W, Randall H, Johnson D, Lanier A, Punaro M, Wittkowski KM, White P, Fay J, Klintmalm G, Ramilo O, Palucka AK, Banchereau J, Pascual V. Chaussabel D, et al. Immunity. 2008 Jul 18;29(1):150-64. doi: 10.1016/j.immuni.2008.05.012. Immunity. 2008. PMID: 18631455 Free PMC article.
22 results