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24 results

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Page 1
Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D.
Arora P, Zhang L, Nehlmeier I, Kempf A, Graichen L, Kreitz E, Sidarovich A, Rocha C, Gärtner S, Winkler M, Schulz S, Jäck H-M, Hoffmann M, Pöhlmann S. Arora P, et al. Among authors: graichen l. J Virol. 2025 Jan 10:e0123024. doi: 10.1128/jvi.01230-24. Online ahead of print. J Virol. 2025. PMID: 39791910 Free article.
ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization.
Zhang L, Cheng HH, Krüger N, Hörnich B, Graichen L, Hahn AS, Schulz SR, Jäck HM, Stankov MV, Behrens GMN, Müller MA, Drosten C, Mörer O, Winkler MS, Qian Z, Pöhlmann S, Hoffmann M. Zhang L, et al. Among authors: graichen l. PLoS Pathog. 2024 Nov 13;20(11):e1012653. doi: 10.1371/journal.ppat.1012653. eCollection 2024 Nov. PLoS Pathog. 2024. PMID: 39536058 Free PMC article.
Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage.
Zhang L, Dopfer-Jablonka A, Nehlmeier I, Kempf A, Graichen L, Calderón Hampel N, Cossmann A, Stankov MV, Morillas Ramos G, Schulz SR, Jäck HM, Behrens GMN, Pöhlmann S, Hoffmann M. Zhang L, et al. Among authors: graichen l. Vaccines (Basel). 2024 May 1;12(5):487. doi: 10.3390/vaccines12050487. Vaccines (Basel). 2024. PMID: 38793739 Free PMC article.
SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency.
Zhang L, Kempf A, Nehlmeier I, Cossmann A, Richter A, Bdeir N, Graichen L, Moldenhauer AS, Dopfer-Jablonka A, Stankov MV, Simon-Loriere E, Schulz SR, Jäck HM, Čičin-Šain L, Behrens GMN, Drosten C, Hoffmann M, Pöhlmann S. Zhang L, et al. Among authors: graichen l. Cell. 2024 Feb 1;187(3):596-608.e17. doi: 10.1016/j.cell.2023.12.025. Epub 2024 Jan 8. Cell. 2024. PMID: 38194966
The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant.
Arora P, Zhang L, Rocha C, Graichen L, Nehlmeier I, Kempf A, Cossmann A, Ramos GM, Baier E, Tampe B, Moerer O, Dickel S, Winkler MS, Behrens GMN, Pöhlmann S, Hoffmann M. Arora P, et al. Among authors: graichen l. Int J Mol Sci. 2022 Nov 14;23(22):14057. doi: 10.3390/ijms232214057. Int J Mol Sci. 2022. PMID: 36430535 Free PMC article.
Host Cell Entry and Neutralization Sensitivity of SARS-CoV-2 Lineages B.1.620 and R.1.
Sidarovich A, Krüger N, Rocha C, Graichen L, Kempf A, Nehlmeier I, Lier M, Cossmann A, Stankov MV, Schulz SR, Behrens GMN, Jäck HM, Pöhlmann S, Hoffmann M. Sidarovich A, et al. Among authors: graichen l. Viruses. 2022 Nov 9;14(11):2475. doi: 10.3390/v14112475. Viruses. 2022. PMID: 36366573 Free PMC article.
SARS-CoV-2 Omicron sublineages show comparable cell entry but differential neutralization by therapeutic antibodies.
Arora P, Zhang L, Krüger N, Rocha C, Sidarovich A, Schulz S, Kempf A, Graichen L, Moldenhauer AS, Cossmann A, Dopfer-Jablonka A, Behrens GMN, Jäck HM, Pöhlmann S, Hoffmann M. Arora P, et al. Among authors: graichen l. Cell Host Microbe. 2022 Aug 10;30(8):1103-1111.e6. doi: 10.1016/j.chom.2022.04.017. Epub 2022 May 6. Cell Host Microbe. 2022. PMID: 35588741 Free PMC article.
24 results