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Longitudinal analysis of serum-derived extracellular vesicle RNA to monitor dacomitinib treatment response in EGFR-amplified recurrent glioblastoma patients.
Yekula A, Hsia T, Kitchen RR, Chakrabortty SK, Yu W, Batool SM, Lewis B, Szeglowski AJ, Weissleder R, Lee H, Chi AS, Batchelor T, Carter BS, Breakefield XO, Skog J, Balaj L. Yekula A, et al. Among authors: breakefield xo. Neurooncol Adv. 2023 Sep 4;5(1):vdad104. doi: 10.1093/noajnl/vdad104. eCollection 2023 Jan-Dec. Neurooncol Adv. 2023. PMID: 37811539 Free PMC article.
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW. Welsh JA, et al. J Extracell Vesicles. 2024 Feb;13(2):e12404. doi: 10.1002/jev2.12404. J Extracell Vesicles. 2024. PMID: 38326288 Free PMC article.
Roles of extracellular vesicles in glioblastoma: foes, friends and informers.
Lunavat TR, Nieland L, Vrijmoet AB, Zargani-Piccardi A, Samaha Y, Breyne K, Breakefield XO. Lunavat TR, et al. Among authors: breakefield xo. Front Oncol. 2023 Nov 24;13:1291177. doi: 10.3389/fonc.2023.1291177. eCollection 2023. Front Oncol. 2023. PMID: 38074665 Free PMC article. Review.
CRISPR targeting of mmu-miR-21a through a single adeno-associated virus vector prolongs survival of glioblastoma-bearing mice.
Nieland L, Vrijmoet AB, Jetten IW, Rufino-Ramos D, de Reus AJEM, Breyne K, Kleinstiver BP, Maguire CA, Broekman MLD, Breakefield XO, Abels ER. Nieland L, et al. Among authors: breakefield xo. Mol Ther. 2024 Nov 19:S1525-0016(24)00750-0. doi: 10.1016/j.ymthe.2024.11.023. Online ahead of print. Mol Ther. 2024. PMID: 39563028 Free article.
Engineered EVs designed to target diseases of the CNS.
Nieland L, Mahjoum S, Grandell E, Breyne K, Breakefield XO. Nieland L, et al. Among authors: breakefield xo. J Control Release. 2023 Apr;356:493-506. doi: 10.1016/j.jconrel.2023.03.009. Epub 2023 Mar 15. J Control Release. 2023. PMID: 36907561 Free PMC article. Review.
Heparin interferes with the uptake of liposomes in glioma.
van Solinge TS, Friis KP, O'Brien K, Verschoor RL, van Aarle J, Koekman A, Breakefield XO, Vader P, Schiffelers R, Broekman M. van Solinge TS, et al. Among authors: breakefield xo. Int J Pharm X. 2023 Jun 21;6:100191. doi: 10.1016/j.ijpx.2023.100191. eCollection 2023 Dec 15. Int J Pharm X. 2023. PMID: 37408568 Free PMC article.
Extracellular communication between brain cells through functional transfer of Cre mRNA.
Rufino-Ramos D, Leandro K, Perdigão PRL, O'Brien K, Pinto MM, Santana MM, van Solinge TS, Mahjoum S, Breakefield XO, Breyne K, de Almeida LP. Rufino-Ramos D, et al. Among authors: breakefield xo. bioRxiv [Preprint]. 2023 Jan 31:2023.01.29.525937. doi: 10.1101/2023.01.29.525937. bioRxiv. 2023. Update in: Mol Ther. 2023 Jul 5;31(7):2220-2239. doi: 10.1016/j.ymthe.2023.05.012 PMID: 36811091 Free PMC article. Updated. Preprint.
462 results