George RF - Search Results

1

Exploration of thiazolidine-2,4-diones as tyrosine kinase inhibitors: Design, synthesis, ADMET, docking, and antiproliferative evaluations.

Aziz NAAM, George RF, El-Adl K, Mahmoud WR. Aziz NAAM, et al. Among authors: george rf. Arch Pharm (Weinheim). 2023 Mar;356(3):e2200465. doi: 10.1002/ardp.202200465. Epub 2022 Nov 20. Arch Pharm (Weinheim). 2023. PMID: 36403198

2

Synthesis, antitumor activity evaluation, and DNA-binding study of coumarin-based agents.

Amin KM, Taha AM, George RF, Mohamed NM, Elsenduny FF. Amin KM, et al. Among authors: george rf. Arch Pharm (Weinheim). 2018 Jan;351(1). doi: 10.1002/ardp.201700199. Epub 2017 Nov 17. Arch Pharm (Weinheim). 2018. PMID: 29148081

3

Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors.

Hassan GS, Georgey HH, Mohammed EZ, George RF, Mahmoud WR, Omar FA. Hassan GS, et al. Among authors: george rf. Eur J Med Chem. 2021 Jun 5;218:113389. doi: 10.1016/j.ejmech.2021.113389. Epub 2021 Mar 18. Eur J Med Chem. 2021. PMID: 33784602

4

Design, synthesis, and pharmacological characterization of some 2-substituted-3-phenyl-quinazolin-4(3H)-one derivatives as phosphodiesterase inhibitors.

Amin KM, Hegazy GH, George RF, Ibrahim NR, Mohamed NM. Amin KM, et al. Among authors: george rf. Arch Pharm (Weinheim). 2021 Sep;354(9):e2100051. doi: 10.1002/ardp.202100051. Epub 2021 May 11. Arch Pharm (Weinheim). 2021. PMID: 33977557

5

Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs).

Mohammed EZ, Mahmoud WR, George RF, Hassan GS, Omar FA, Georgey HH. Mohammed EZ, et al. Among authors: george rf. Bioorg Chem. 2021 Nov;116:105347. doi: 10.1016/j.bioorg.2021.105347. Epub 2021 Sep 11. Bioorg Chem. 2021. PMID: 34555628

6

Design, synthesis, in silico docking, ADMET and anticancer evaluations of thiazolidine-2,4-diones bearing heterocyclic rings as dual VEGFR-2/EGFR^T790M tyrosine kinase inhibitors.

Aziz NAAM, George RF, El-Adl K, Mahmoud WR. Aziz NAAM, et al. Among authors: george rf. RSC Adv. 2022 Apr 27;12(20):12913-12931. doi: 10.1039/d2ra01119k. eCollection 2022 Apr 22. RSC Adv. 2022. PMID: 35496328 Free PMC article.

7

Insight on Some Newly Synthesized Trisubstituted Imidazolinones as VEGFR-2 Inhibitors.

Mohamed MR, Mahmoud WR, Refaey RH, George RF, Georgey HH. Mohamed MR, et al. Among authors: george rf. ACS Med Chem Lett. 2024 May 29;15(6):892-898. doi: 10.1021/acsmedchemlett.4c00095. eCollection 2024 Jun 13. ACS Med Chem Lett. 2024. PMID: 38894896

8

Discovery of pyrazole-based analogs as CDK2 inhibitors with apoptotic-inducing activity: design, synthesis and molecular dynamics study.

Ali GME, Ewida MA, Elmetwali AM, Ewida HA, George RF, Mahmoud WR, Ismail NSM, Ahmed MS, Georgey HH. Ali GME, et al. Among authors: george rf. RSC Adv. 2024 Oct 29;14(47):34537-34555. doi: 10.1039/d4ra06500j. eCollection 2024 Oct 29. RSC Adv. 2024. PMID: 39479486 Free PMC article.

9

Facile synthesis of simple 2-oxindole-based compounds with promising antiproliferative activity.

George RF. George RF. Future Med Chem. 2018 Feb;10(3):269-282. doi: 10.4155/fmc-2017-0148. Epub 2018 Jan 15. Future Med Chem. 2018. PMID: 29334243

10

New 1-phthalazinone Scaffold based Compounds: Design, Synthesis, Cytotoxicity and Protein Kinase Inhibition Activity.

Abo-Elmagd NE, George RF, Ezzat MA, Arafa RK. Abo-Elmagd NE, et al. Among authors: george rf. Mini Rev Med Chem. 2018;18(20):1759-1774. doi: 10.2174/1389557518666180903153254. Mini Rev Med Chem. 2018. PMID: 30179133

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