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Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity.
Bondareva O, Rodríguez-Aguilera JR, Oliveira F, Liao L, Rose A, Gupta A, Singh K, Geier F, Schuster J, Boeckel JN, Buescher JM, Kohli S, Klöting N, Isermann B, Blüher M, Sheikh BN. Bondareva O, et al. Among authors: boeckel jn. Nat Metab. 2022 Nov;4(11):1591-1610. doi: 10.1038/s42255-022-00674-x. Epub 2022 Nov 18. Nat Metab. 2022. PMID: 36400935 Free PMC article.
Novel Nongenetic Murine Model of Hyperglycemia and Hyperlipidemia-Associated Aggravated Atherosclerosis.
Gaul S, Shahzad K, Medert R, Gadi I, Mäder C, Schumacher D, Wirth A, Ambreen S, Fatima S, Boeckel JN, Khawaja H, Haas J, Brune M, Nawroth PP, Isermann B, Laufs U, Freichel M. Gaul S, et al. Among authors: boeckel jn. Front Cardiovasc Med. 2022 Mar 8;9:813215. doi: 10.3389/fcvm.2022.813215. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35350534 Free PMC article.
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs.
Kokot KE, Kneuer JM, John D, Rebs S, Möbius-Winkler MN, Erbe S, Müller M, Andritschke M, Gaul S, Sheikh BN, Haas J, Thiele H, Müller OJ, Hille S, Leuschner F, Dimmeler S, Streckfuss-Bömeke K, Meder B, Laufs U, Boeckel JN. Kokot KE, et al. Among authors: boeckel jn. Basic Res Cardiol. 2022 Jun 23;117(1):32. doi: 10.1007/s00395-022-00940-9. Basic Res Cardiol. 2022. PMID: 35737129 Free PMC article.
Leptin treatment has vasculo-protective effects in lipodystrophic mice.
Stürzebecher PE, Kralisch S, Schubert MR, Filipova V, Hoffmann A, Oliveira F, Sheikh BN, Blüher M, Kogel A, Scholz M, Kokot KE, Erbe S, Kneuer JM, Ebert T, Fasshauer M, Miehle K, Laufs U, Tönjes A, Boeckel JN. Stürzebecher PE, et al. Among authors: boeckel jn. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2110374119. doi: 10.1073/pnas.2110374119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161905 Free PMC article.
Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.
Stellos K, Gatsiou A, Stamatelopoulos K, Perisic Matic L, John D, Lunella FF, Jaé N, Rossbach O, Amrhein C, Sigala F, Boon RA, Fürtig B, Manavski Y, You X, Uchida S, Keller T, Boeckel JN, Franco-Cereceda A, Maegdefessel L, Chen W, Schwalbe H, Bindereif A, Eriksson P, Hedin U, Zeiher AM, Dimmeler S. Stellos K, et al. Among authors: boeckel jn. Nat Med. 2016 Oct;22(10):1140-1150. doi: 10.1038/nm.4172. Epub 2016 Sep 5. Nat Med. 2016. PMID: 27595325
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