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Page 1
Nonstop mRNAs generate a ground state of mitochondrial gene expression noise.
Ng KY, Lutfullahoglu Bal G, Richter U, Safronov O, Paulin L, Dunn CD, Paavilainen VO, Richer J, Newman WG, Taylor RW, Battersby BJ. Ng KY, et al. Among authors: paavilainen vo. Sci Adv. 2022 Nov 16;8(46):eabq5234. doi: 10.1126/sciadv.abq5234. Epub 2022 Nov 18. Sci Adv. 2022. PMID: 36399564 Free PMC article.
Mycolactone subverts immunity by selectively blocking the Sec61 translocon.
Baron L, Paatero AO, Morel JD, Impens F, Guenin-Macé L, Saint-Auret S, Blanchard N, Dillmann R, Niang F, Pellegrini S, Taunton J, Paavilainen VO, Demangel C. Baron L, et al. Among authors: paavilainen vo. J Exp Med. 2016 Dec 12;213(13):2885-2896. doi: 10.1084/jem.20160662. Epub 2016 Nov 7. J Exp Med. 2016. PMID: 27821549 Free PMC article.
Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins.
Tranter D, Paatero AO, Kawaguchi S, Kazemi S, Serrill JD, Kellosalo J, Vogel WK, Richter U, Mattos DR, Wan X, Thornburg CC, Oishi S, McPhail KL, Ishmael JE, Paavilainen VO. Tranter D, et al. Among authors: paavilainen vo. ACS Chem Biol. 2020 Aug 21;15(8):2125-2136. doi: 10.1021/acschembio.0c00325. Epub 2020 Jul 20. ACS Chem Biol. 2020. PMID: 32608972 Free PMC article.
Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.
Karki S, Javanainen M, Rehan S, Tranter D, Kellosalo J, Huiskonen JT, Happonen L, Paavilainen V. Karki S, et al. EMBO Rep. 2023 Dec 6;24(12):e57910. doi: 10.15252/embr.202357910. Epub 2023 Nov 20. EMBO Rep. 2023. PMID: 37983950 Free PMC article.
Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW. Kelly JJ, et al. Among authors: paavilainen vo. Nat Struct Mol Biol. 2022 May;29(5):420-429. doi: 10.1038/s41594-022-00755-1. Epub 2022 Apr 21. Nat Struct Mol Biol. 2022. PMID: 35449234 Free PMC article.
37 results