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IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.
Evnouchidou I, Chappert P, Benadda S, Zucchetti A, Weimershaus M, Bens M, Caillens V, Koumantou D, Lotersztajn S, van Endert P, Davoust J, Guermonprez P, Hivroz C, Gross DA, Saveanu L. Evnouchidou I, et al. Among authors: koumantou d. Nat Commun. 2020 Jun 2;11(1):2779. doi: 10.1038/s41467-020-16471-7. Nat Commun. 2020. PMID: 32487999 Free PMC article.
Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin.
Vourloumis D, Mavridis I, Athanasoulis A, Temponeras I, Koumantou D, Giastas P, Mpakali A, Magrioti V, Leib J, van Endert P, Stratikos E, Papakyriakou A. Vourloumis D, et al. Among authors: koumantou d. J Med Chem. 2022 Jul 28;65(14):10098-10117. doi: 10.1021/acs.jmedchem.2c00904. Epub 2022 Jul 14. J Med Chem. 2022. PMID: 35833347
Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1).
Koumantou D, Barnea E, Martin-Esteban A, Maben Z, Papakyriakou A, Mpakali A, Kokkala P, Pratsinis H, Georgiadis D, Stern LJ, Admon A, Stratikos E. Koumantou D, et al. Cancer Immunol Immunother. 2019 Aug;68(8):1245-1261. doi: 10.1007/s00262-019-02358-0. Epub 2019 Jun 20. Cancer Immunol Immunother. 2019. PMID: 31222486 Free PMC article.
Activating FcγR function depends on endosomal-signaling platforms.
Benadda S, Nugue M, Koumantou D, Bens M, De Luca M, Pellé O, Monteiro RC, Evnouchidou I, Saveanu L. Benadda S, et al. Among authors: koumantou d. iScience. 2023 Jun 9;26(7):107055. doi: 10.1016/j.isci.2023.107055. eCollection 2023 Jul 21. iScience. 2023. PMID: 37360697 Free PMC article.
M1-aminopeptidase family - beyond antigen-trimming activities.
Evnouchidou I, Koumantou D, Nugue M, Saveanu L. Evnouchidou I, et al. Among authors: koumantou d. Curr Opin Immunol. 2023 Aug;83:102337. doi: 10.1016/j.coi.2023.102337. Epub 2023 May 20. Curr Opin Immunol. 2023. PMID: 37216842 Review.
15 results