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SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression.
Niemeyer D, Stenzel S, Veith T, Schroeder S, Friedmann K, Weege F, Trimpert J, Heinze J, Richter A, Jansen J, Emanuel J, Kazmierski J, Pott F, Jeworowski LM, Olmer R, Jaboreck MC, Tenner B, Papies J, Walper F, Schmidt ML, Heinemann N, Möncke-Buchner E, Baumgardt M, Hoffmann K, Widera M, Thao TTN, Balázs A, Schulze J, Mache C, Jones TC, Morkel M, Ciesek S, Hanitsch LG, Mall MA, Hocke AC, Thiel V, Osterrieder K, Wolff T, Martin U, Corman VM, Müller MA, Goffinet C, Drosten C. Niemeyer D, et al. Among authors: wolff t. PLoS Biol. 2022 Nov 16;20(11):e3001871. doi: 10.1371/journal.pbio.3001871. eCollection 2022 Nov. PLoS Biol. 2022. PMID: 36383605 Free PMC article.
Influenza A viruses target type II pneumocytes in the human lung.
Weinheimer VK, Becher A, Tönnies M, Holland G, Knepper J, Bauer TT, Schneider P, Neudecker J, Rückert JC, Szymanski K, Temmesfeld-Wollbrueck B, Gruber AD, Bannert N, Suttorp N, Hippenstiel S, Wolff T, Hocke AC. Weinheimer VK, et al. Among authors: wolff t. J Infect Dis. 2012 Dec 1;206(11):1685-94. doi: 10.1093/infdis/jis455. Epub 2012 Jul 24. J Infect Dis. 2012. PMID: 22829640 Free PMC article.
Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections.
Corman VM, Müller MA, Costabel U, Timm J, Binger T, Meyer B, Kreher P, Lattwein E, Eschbach-Bludau M, Nitsche A, Bleicker T, Landt O, Schweiger B, Drexler JF, Osterhaus AD, Haagmans BL, Dittmer U, Bonin F, Wolff T, Drosten C. Corman VM, et al. Among authors: wolff t. Euro Surveill. 2012 Dec 6;17(49):20334. doi: 10.2807/ese.17.49.20334-en. Euro Surveill. 2012. PMID: 23231891 Free article.
Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs.
Hocke AC, Becher A, Knepper J, Peter A, Holland G, Tönnies M, Bauer TT, Schneider P, Neudecker J, Muth D, Wendtner CM, Rückert JC, Drosten C, Gruber AD, Laue M, Suttorp N, Hippenstiel S, Wolff T. Hocke AC, et al. Among authors: wolff t. Am J Respir Crit Care Med. 2013 Oct 1;188(7):882-6. doi: 10.1164/rccm.201305-0954LE. Am J Respir Crit Care Med. 2013. PMID: 24083868 No abstract available.
Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry.
Lauster D, Klenk S, Ludwig K, Nojoumi S, Behren S, Adam L, Stadtmüller M, Saenger S, Zimmler S, Hönzke K, Yao L, Hoffmann U, Bardua M, Hamann A, Witzenrath M, Sander LE, Wolff T, Hocke AC, Hippenstiel S, De Carlo S, Neudecker J, Osterrieder K, Budisa N, Netz RR, Böttcher C, Liese S, Herrmann A, Hackenberger CPR. Lauster D, et al. Among authors: wolff t. Nat Nanotechnol. 2020 May;15(5):373-379. doi: 10.1038/s41565-020-0660-2. Epub 2020 Mar 30. Nat Nanotechnol. 2020. PMID: 32231271
Variable Sensitivity of SARS-CoV-2 Molecular Detection in European Expert Laboratories: External Quality Assessment, June and July 2020.
Fischer C, Mögling R, Melidou A, Kühne A, Oliveira-Filho EF, Wolff T, Reiche J, Broberg E, Drosten C, Meijer A, Leitmeyer K, Drexler JF, Reusken CBEM. Fischer C, et al. Among authors: wolff t. J Clin Microbiol. 2021 Feb 18;59(3):e02676-20. doi: 10.1128/JCM.02676-20. Print 2021 Feb 18. J Clin Microbiol. 2021. PMID: 33298612 Free PMC article.
552 results