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Page 1
Experimental and In Silico Analysis of TEM β-Lactamase Adaptive Evolution.
Standley M, Blay V, Beleva Guthrie V, Kim J, Lyman A, Moya A, Karchin R, Camps M. Standley M, et al. Among authors: karchin r. ACS Infect Dis. 2022 Dec 9;8(12):2451-2463. doi: 10.1021/acsinfecdis.2c00216. Epub 2022 Nov 14. ACS Infect Dis. 2022. PMID: 36377311 Free PMC article.
Poly (ADP-ribose) Polymerase Inhibitor Resistance Driven by Emergence of Polyclonal Mutations With Convergent Evolution: A Molecular Tumor Board Discussion.
Fatteh M, Wehr J, Karaindrou K, Xian RR, Gocke C, Lin MT, Petry D, Visvanathan K, Couzi R, Santa Maria C, Stearns V, Tao JJ, Anagnostou V, Canzoniero JV; and the Johns Hopkins Molecular Tumor Board; Johns Hopkins Molecular Tumor Board. Fatteh M, et al. JCO Precis Oncol. 2024 Oct;8:e2400254. doi: 10.1200/PO.24.00254. Epub 2024 Oct 11. JCO Precis Oncol. 2024. PMID: 39393037 Free PMC article.
Druggable genomic landscapes of high-grade gliomas.
Ghanem P, Fatteh M, Kamson DO, Balan A, Chang M, Tao J, Blakeley J; Johns Hopkins Molecular Tumor Board Investigators; Canzoniero J, Grossman SA, Marrone K, Schreck KC, Anagnostou V. Ghanem P, et al. Front Med (Lausanne). 2023 Dec 8;10:1254955. doi: 10.3389/fmed.2023.1254955. eCollection 2023. Front Med (Lausanne). 2023. PMID: 38143440 Free PMC article.
Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer.
Mistretta B, Rankothgedera S, Castillo M, Rao M, Holloway K, Bhardwaj A, El Noafal M, Albarracin C, El-Zein R, Rezaei H, Su X, Akbani R, Shao XM, Czerniecki BJ, Karchin R, Bedrosian I, Gunaratne PH. Mistretta B, et al. Among authors: karchin r. Front Immunol. 2023 Sep 6;14:1188831. doi: 10.3389/fimmu.2023.1188831. eCollection 2023. Front Immunol. 2023. PMID: 37744342 Free PMC article.
Islands of genomic stability in the face of genetically unstable metastatic cancer.
Bowland K, Lai J, Skaist A, Zhang Y, Teh SSK, Roberts NJ, Thompson E, Wheelan SJ, Hruban RH, Karchin R, Bailey MH, Iacobuzio-Donahue CA, Eshleman JR. Bowland K, et al. Among authors: karchin r. PLoS One. 2024 Dec 19;19(12):e0298490. doi: 10.1371/journal.pone.0298490. eCollection 2024. PLoS One. 2024. PMID: 39700179 Free PMC article.
SpliceMutr Enables Pan-Cancer Analysis of Splicing-Derived Neoantigen Burden in Tumors.
Palmer T, Kessler MD, Shao XM, Balan A, Yarchoan M, Zaidi N, Lopez-Vidal TY, Saeed AM, Gore J, Azad NS, Jaffee EM, Favorov AV, Anagnostou V, Karchin R, Gaykalova DA, Fertig EJ, Danilova L. Palmer T, et al. Among authors: karchin r. Cancer Res Commun. 2024 Dec 1;4(12):3137-3150. doi: 10.1158/2767-9764.CRC-23-0309. Cancer Res Commun. 2024. PMID: 39470352 Free PMC article.
Assessment of the evidence yield for the calibrated PP3/BP4 computational recommendations.
Stenton SL, Pejaver V, Bergquist T, Biesecker LG, Byrne AB, Nadeau EAW, Greenblatt MS, Harrison SM, Tavtigian SV, Radivojac P, Brenner SE, O'Donnell-Luria A; ClinGen Sequence Variant Interpretation Working Group. Stenton SL, et al. Genet Med. 2024 Nov;26(11):101213. doi: 10.1016/j.gim.2024.101213. Epub 2024 Jul 25. Genet Med. 2024. PMID: 39030733
148 results