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GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease.
Senkevich K, Zorca CE, Dworkind A, Rudakou U, Somerville E, Yu E, Ermolaev A, Nikanorova D, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Fahn S, Waters C, Monchi O, Dauvilliers Y, Dupré N, Greenbaum L, Hassin-Baer S, Grenn FP, Chiang MSR, Sardi SP, Vanderperre B, Blauwendraat C, Trempe JF, Fon EA, Durcan TM, Alcalay RN, Gan-Or Z. Senkevich K, et al. Among authors: trempe jf. Brain. 2023 May 2;146(5):1859-1872. doi: 10.1093/brain/awac413. Brain. 2023. PMID: 36370000 Free PMC article.
Unveiling the Molecular Mechanisms of the Type-IX Secretion System's Response Regulator: Structural and Functional Insights.
Saran A, Kim HM, Manning I, Hancock MA, Schmitz C, Madej M, Potempa J, Sola M, Trempe JF, Zhu Y, Davey ME, Zeytuni N. Saran A, et al. Among authors: trempe jf. bioRxiv [Preprint]. 2024 May 15:2024.05.15.594396. doi: 10.1101/2024.05.15.594396. bioRxiv. 2024. Update in: PNAS Nexus. 2024 Jul 31;3(8):pgae316. doi: 10.1093/pnasnexus/pgae316. PMID: 38798656 Free PMC article. Updated. Preprint.
Mechanism of parkin activation by phosphorylation.
Sauvé V, Sung G, Soya N, Kozlov G, Blaimschein N, Miotto LS, Trempe JF, Lukacs GL, Gehring K. Sauvé V, et al. Among authors: trempe jf. Nat Struct Mol Biol. 2018 Jul;25(7):623-630. doi: 10.1038/s41594-018-0088-7. Epub 2018 Jul 2. Nat Struct Mol Biol. 2018. PMID: 29967542
Publisher Correction: Mechanism of parkin activation by phosphorylation.
Sauvé V, Sung G, Soya N, Kozlov G, Blaimschein N, Miotto LS, Trempe JF, Lukacs GL, Gehring K. Sauvé V, et al. Among authors: trempe jf. Nat Struct Mol Biol. 2018 Aug;25(8):744. doi: 10.1038/s41594-018-0105-x. Nat Struct Mol Biol. 2018. PMID: 30026521
84 results