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Surgical results of the Lung Cancer Mutation Consortium 3 trial: A phase II multicenter single-arm study to investigate the efficacy and safety of atezolizumab as neoadjuvant therapy in patients with stages IB-select IIIB resectable non-small cell lung cancer.
Rusch VW, Nicholas A, Patterson GA, Waqar SN, Toloza EM, Haura EB, Raz DJ, Reckamp KL, Merritt RE, Owen DH, Finley DJ, McNamee CJ, Blasberg JD, Garon EB, Mitchell JD, Doebele RC, Baciewicz F, Nagasaka M, Pass HI, Schulze K, Johnson A, Bunn PA, Johnson BE, Kris MG, Kwiatkowski DJ, Wistuba II, Chaft JE, Carbone DP, Lee JM. Rusch VW, et al. Among authors: doebele rc. J Thorac Cardiovasc Surg. 2023 Mar;165(3):828-839.e5. doi: 10.1016/j.jtcvs.2022.10.007. Epub 2022 Oct 8. J Thorac Cardiovasc Surg. 2023. PMID: 36369159 Free PMC article. Clinical Trial.
TRKing down an old oncogene in a new era of targeted therapy.
Vaishnavi A, Le AT, Doebele RC. Vaishnavi A, et al. Among authors: doebele rc. Cancer Discov. 2015 Jan;5(1):25-34. doi: 10.1158/2159-8290.CD-14-0765. Epub 2014 Dec 19. Cancer Discov. 2015. PMID: 25527197 Free PMC article. Review.
Accessory molecules for MHC class II peptide loading.
Busch R, Doebele RC, Patil NS, Pashine A, Mellins ED. Busch R, et al. Among authors: doebele rc. Curr Opin Immunol. 2000 Feb;12(1):99-106. doi: 10.1016/s0952-7915(99)00057-6. Curr Opin Immunol. 2000. PMID: 10679402 Review.
Targeted inhibition of the molecular chaperone Hsp90 overcomes ALK inhibitor resistance in non-small cell lung cancer.
Sang J, Acquaviva J, Friedland JC, Smith DL, Sequeira M, Zhang C, Jiang Q, Xue L, Lovly CM, Jimenez JP, Shaw AT, Doebele RC, He S, Bates RC, Camidge DR, Morris SW, El-Hariry I, Proia DA. Sang J, et al. Among authors: doebele rc. Cancer Discov. 2013 Apr;3(4):430-43. doi: 10.1158/2159-8290.CD-12-0440. Epub 2013 Mar 26. Cancer Discov. 2013. PMID: 23533265 Free PMC article. Clinical Trial.
A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis.
Doebele RC, Schulze-Hoepfner FT, Hong J, Chlenski A, Zeitlin BD, Goel K, Gomes S, Liu Y, Abe MK, Nor JE, Lingen MW, Rosner MR. Doebele RC, et al. Blood. 2009 Nov 12;114(20):4592-600. doi: 10.1182/blood-2009-04-217042. Epub 2009 Aug 26. Blood. 2009. PMID: 19710505 Free PMC article.
161 results