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Page 1
Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies.
Khan AO, Rodriguez-Romera A, Reyat JS, Olijnik AA, Colombo M, Wang G, Wen WX, Sousos N, Murphy LC, Grygielska B, Perrella G, Mahony CB, Ling RE, Elliott NE, Karali CS, Stone AP, Kemble S, Cutler EA, Fielding AK, Croft AP, Bassett D, Poologasundarampillai G, Roy A, Gooding S, Rayes J, Machlus KR, Psaila B. Khan AO, et al. Among authors: elliott ne. Cancer Discov. 2023 Feb 6;13(2):364-385. doi: 10.1158/2159-8290.CD-22-0199. Cancer Discov. 2023. PMID: 36351055 Free PMC article.
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
Louka E, Povinelli B, Rodriguez-Meira A, Buck G, Wen WX, Wang G, Sousos N, Ashley N, Hamblin A, Booth CAG, Roy A, Elliott N, Iskander D, de la Fuente J, Fordham N, O'Byrne S, Inglott S, Norfo R, Salio M, Thongjuea S, Rao A, Roberts I, Mead AJ. Louka E, et al. J Exp Med. 2021 Feb 1;218(2):e20180853. doi: 10.1084/jem.20180853. J Exp Med. 2021. PMID: 33416891 Free PMC article.
Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.
O'Byrne S, Elliott N, Rice S, Buck G, Fordham N, Garnett C, Godfrey L, Crump NT, Wright G, Inglott S, Hua P, Psaila B, Povinelli B, Knapp DJHF, Agraz-Doblas A, Bueno C, Varela I, Bennett P, Koohy H, Watt SM, Karadimitris A, Mead AJ, Ancliff P, Vyas P, Menendez P, Milne TA, Roberts I, Roy A. O'Byrne S, et al. Blood. 2019 Sep 26;134(13):1059-1071. doi: 10.1182/blood.2019001289. Epub 2019 Aug 5. Blood. 2019. PMID: 31383639 Free article.
Blood and immune development in human fetal bone marrow and Down syndrome.
Jardine L, Webb S, Goh I, Quiroga Londoño M, Reynolds G, Mather M, Olabi B, Stephenson E, Botting RA, Horsfall D, Engelbert J, Maunder D, Mende N, Murnane C, Dann E, McGrath J, King H, Kucinski I, Queen R, Carey CD, Shrubsole C, Poyner E, Acres M, Jones C, Ness T, Coulthard R, Elliott N, O'Byrne S, Haltalli MLR, Lawrence JE, Lisgo S, Balogh P, Meyer KB, Prigmore E, Ambridge K, Jain MS, Efremova M, Pickard K, Creasey T, Bacardit J, Henderson D, Coxhead J, Filby A, Hussain R, Dixon D, McDonald D, Popescu DM, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Regev A, Behjati S, Laurenti E, Wilson NK, Roy A, Göttgens B, Roberts I, Teichmann SA, Haniffa M. Jardine L, et al. Nature. 2021 Oct;598(7880):327-331. doi: 10.1038/s41586-021-03929-x. Epub 2021 Sep 29. Nature. 2021. PMID: 34588693 Free PMC article.
A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program.
Rice S, Jackson T, Crump NT, Fordham N, Elliott N, O'Byrne S, Fanego MDML, Addy D, Crabb T, Dryden C, Inglott S, Ladon D, Wright G, Bartram J, Ancliff P, Mead AJ, Halsey C, Roberts I, Milne TA, Roy A. Rice S, et al. Nat Commun. 2021 Nov 25;12(1):6905. doi: 10.1038/s41467-021-27270-z. Nat Commun. 2021. PMID: 34824279 Free PMC article.
H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells.
Godfrey L, Crump NT, O'Byrne S, Lau IJ, Rice S, Harman JR, Jackson T, Elliott N, Buck G, Connor C, Thorne R, Knapp DJHF, Heidenreich O, Vyas P, Menendez P, Inglott S, Ancliff P, Geng H, Roberts I, Roy A, Milne TA. Godfrey L, et al. Leukemia. 2021 Jan;35(1):90-106. doi: 10.1038/s41375-020-0808-y. Epub 2020 Apr 2. Leukemia. 2021. PMID: 32242051 Free PMC article.
Epigenome-wide association study of acute lymphoblastic leukemia in children with Down syndrome.
Li S, Sok P, Xu K, Muskens IS, Elliott N, Myint SS, Pandey P, Hansen HM, Morimoto LM, Kang AY, Metayer C, Ma X, Mueller BA, Roy A, Roberts I, Rabin KR, Brown AL, Lupo PJ, Wiemels JL, de Smith AJ. Li S, et al. Blood Adv. 2022 Jul 26;6(14):4132-4136. doi: 10.1182/bloodadvances.2022007098. Blood Adv. 2022. PMID: 35588500 Free PMC article. No abstract available.
13 results