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Reversal and Preventive Pleiotropic Mechanisms Involved in the Antipsychotic-Like Effect of Taurine, an Essential β-Amino Acid in Ketamine-Induced Experimental Schizophrenia in Mice.
Ben-Azu B, Uruaka CI, Ajayi AM, Jarikre TA, Nwangwa KE, Chilaka KC, Chijioke BS, Omonyeme MG, Ozege CB, Ofili EC, Warekoromor EB, Edigbue NL, Esiekpe UV, Akaenyi DE, Agu GO. Ben-Azu B, et al. Among authors: chijioke bs. Neurochem Res. 2023 Mar;48(3):816-829. doi: 10.1007/s11064-022-03808-5. Epub 2022 Nov 9. Neurochem Res. 2023. PMID: 36350433
Taurine, an essential β-amino acid insulates against ketamine-induced experimental psychosis by enhancement of cholinergic neurotransmission, inhibition of oxidative/nitrergic imbalances, and suppression of COX-2/iNOS immunoreactions in mice.
Ben-Azu B, Adebayo OG, Jarikre TA, Oyovwi MO, Edje KE, Omogbiya IA, Eduviere AT, Moke EG, Chijioke BS, Odili OS, Omondiabge OP, Oyovbaire A, Esuku DT, Ozah EO, Japhet K. Ben-Azu B, et al. Among authors: chijioke bs. Metab Brain Dis. 2022 Dec;37(8):2807-2826. doi: 10.1007/s11011-022-01075-5. Epub 2022 Sep 3. Metab Brain Dis. 2022. PMID: 36057735