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Page 1
A Large-Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands.
den Heijer JM, Cullen VC, Quadri M, Schmitz A, Hilt DC, Lansbury P, Berendse HW, van de Berg WDJ, de Bie RMA, Boertien JM, Boon AJW, Contarino MF, van Hilten JJ, Hoff JI, van Mierlo T, Munts AG, van der Plas AA, Ponsen MM, Baas F, Majoor-Krakauer D, Bonifati V, van Laar T, Groeneveld GJ. den Heijer JM, et al. Mov Disord. 2020 Sep;35(9):1667-1674. doi: 10.1002/mds.28112. Epub 2020 Jul 2. Mov Disord. 2020. PMID: 32618053 Free PMC article.
Experience in Genetic Counseling for GBA1 Variants in Parkinson's Disease.
den Heijer JM, van Hilten JJ, Kievit AJA, Bonifati V, Groeneveld GJ. den Heijer JM, et al. Mov Disord Clin Pract. 2020 Oct 27;8(1):33-36. doi: 10.1002/mdc3.13098. eCollection 2021 Jan. Mov Disord Clin Pract. 2020. PMID: 33426156 Free PMC article. No abstract available.
A randomized single and multiple ascending dose study in healthy volunteers of LTI-291, a centrally penetrant glucocerebrosidase activator.
den Heijer JM, Kruithof AC, van Amerongen G, de Kam ML, Thijssen E, Grievink HW, Moerland M, Walker M, Been K, Skerlj R, Justman C, Dudgeon L, Lansbury P, Cullen VC, Hilt DC, Groeneveld GJ. den Heijer JM, et al. Br J Clin Pharmacol. 2021 Sep;87(9):3561-3573. doi: 10.1111/bcp.14772. Epub 2021 Mar 2. Br J Clin Pharmacol. 2021. PMID: 33576113 Free PMC article.
A Randomized Trial Assessing the Safety, Pharmacokinetics, and Efficacy During Morning Off of AZ-009.
Thijssen E, den Heijer J, Puibert D, Moss L, Lei M, Hasegawa D, Keum K, Mochel K, Ezzeldin Sharaf M, Alfredson T, Zeng W, van Brummelen E, Naranda T, Groeneveld GJ. Thijssen E, et al. Among authors: den heijer j. Mov Disord. 2022 Apr;37(4):790-798. doi: 10.1002/mds.28926. Epub 2022 Jan 20. Mov Disord. 2022. PMID: 35048423 Free PMC article. Clinical Trial.
Safety and pharmacokinetics of multiple dosing with inhalable apomorphine (AZ-009), and its efficacy in a randomized crossover study in Parkinson's disease patients.
Thijssen E, den Heijer JM, Puibert D, van Brummelen EMJ, Naranda T, Groeneveld GJ. Thijssen E, et al. Among authors: den heijer jm. Parkinsonism Relat Disord. 2022 Apr;97:84-90. doi: 10.1016/j.parkreldis.2022.02.014. Epub 2022 Mar 8. Parkinsonism Relat Disord. 2022. PMID: 35366574 Clinical Trial.
26 results