Zhao LH - Search Results

1

Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor.

Zhao LH, Lin J, Ji SY, Zhou XE, Mao C, Shen DD, He X, Xiao P, Sun J, Melcher K, Zhang Y, Yu X, Xu HE. Zhao LH, et al. Nat Commun. 2022 Nov 5;13(1):6670. doi: 10.1038/s41467-022-33851-3. Nat Commun. 2022. PMID: 36335102 Free PMC article.

2

Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.

Zhao LH, Zhou XE, Wu ZS, Yi W, Xu Y, Li S, Xu TH, Liu Y, Chen RZ, Kovach A, Kang Y, Hou L, He Y, Xie C, Song W, Zhong D, Xu Y, Wang Y, Li J, Zhang C, Melcher K, Xu HE. Zhao LH, et al. Cell Res. 2013 Mar;23(3):436-9. doi: 10.1038/cr.2013.19. Epub 2013 Feb 5. Cell Res. 2013. PMID: 23381136 Free PMC article. No abstract available.

3

DWARF 53 acts as a repressor of strigolactone signalling in rice.

Jiang L, Liu X, Xiong G, Liu H, Chen F, Wang L, Meng X, Liu G, Yu H, Yuan Y, Yi W, Zhao L, Ma H, He Y, Wu Z, Melcher K, Qian Q, Xu HE, Wang Y, Li J. Jiang L, et al. Nature. 2013 Dec 19;504(7480):401-5. doi: 10.1038/nature12870. Epub 2013 Dec 11. Nature. 2013. PMID: 24336200 Free PMC article.

4

Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3.

Zhao LH, Zhou XE, Yi W, Wu Z, Liu Y, Kang Y, Hou L, de Waal PW, Li S, Jiang Y, Scaffidi A, Flematti GR, Smith SM, Lam VQ, Griffin PR, Wang Y, Li J, Melcher K, Xu HE. Zhao LH, et al. Cell Res. 2015 Nov;25(11):1219-36. doi: 10.1038/cr.2015.122. Epub 2015 Oct 16. Cell Res. 2015. PMID: 26470846 Free PMC article.

5

Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.

Zhao LH, Yin Y, Yang D, Liu B, Hou L, Wang X, Pal K, Jiang Y, Feng Y, Cai X, Dai A, Liu M, Wang MW, Melcher K, Xu HE. Zhao LH, et al. J Biol Chem. 2016 Jul 15;291(29):15119-30. doi: 10.1074/jbc.M116.726620. Epub 2016 May 13. J Biol Chem. 2016. PMID: 27226600 Free PMC article.

6

An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain.

Yin Y, Zhou XE, Hou L, Zhao LH, Liu B, Wang G, Jiang Y, Melcher K, Xu HE. Yin Y, et al. Among authors: zhao lh. Cell Discov. 2016 Nov 22;2:16042. doi: 10.1038/celldisc.2016.42. eCollection 2016. Cell Discov. 2016. PMID: 27917297 Free PMC article.

7

Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors.

Yin Y, de Waal PW, He Y, Zhao LH, Yang D, Cai X, Jiang Y, Melcher K, Wang MW, Xu HE. Yin Y, et al. Among authors: zhao lh. J Biol Chem. 2017 Jun 16;292(24):9865-9881. doi: 10.1074/jbc.M117.782987. Epub 2017 Mar 29. J Biol Chem. 2017. PMID: 28356352 Free PMC article.

8

The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine.

Li H, Zhao L, Singh R, Ham JN, Fadoju DO, Bean LJH, Zhang Y, Xu Y, Xu HE, Gambello MJ. Li H, et al. Mol Genet Metab Rep. 2018 Oct 2;17:46-52. doi: 10.1016/j.ymgmr.2018.09.006. eCollection 2018 Dec. Mol Genet Metab Rep. 2018. PMID: 30294546 Free PMC article.

9

Structure and dynamics of the active human parathyroid hormone receptor-1.

Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y. Zhao LH, et al. Science. 2019 Apr 12;364(6436):148-153. doi: 10.1126/science.aav7942. Science. 2019. PMID: 30975883 Free PMC article.

10

Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.

Ma S, Shen Q, Zhao LH, Mao C, Zhou XE, Shen DD, de Waal PW, Bi P, Li C, Jiang Y, Wang MW, Sexton PM, Wootten D, Melcher K, Zhang Y, Xu HE. Ma S, et al. Among authors: zhao lh. Mol Cell. 2020 Feb 6;77(3):669-680.e4. doi: 10.1016/j.molcel.2020.01.013. Epub 2020 Jan 30. Mol Cell. 2020. PMID: 32004470 Free article.

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