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Severe COVID-19 is associated with fungal colonization of the nasopharynx and potent induction of IL-17 responses in the nasal epithelium.
Ziegler CGK, Owings AH, Miao VN, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Pride Y, Abraham GE 3rd, Senitko M, Robinson TO, Lionakis MS, Shalek AK, Ordovas-Montanes J, Horwitz BH, Glover SC. Ziegler CGK, et al. Among authors: tang y. medRxiv [Preprint]. 2022 Oct 26:2022.10.25.22281528. doi: 10.1101/2022.10.25.22281528. medRxiv. 2022. PMID: 36324802 Free PMC article. Preprint.
Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19.
Ziegler CGK, Miao VN, Owings AH, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Christian T, Parker A, Sindel CB, Burger MW, Pride Y, Hasan M, Abraham GE 3rd, Senitko M, Robinson TO, Shalek AK, Glover SC, Horwitz BH, Ordovas-Montanes J. Ziegler CGK, et al. Among authors: tang y. bioRxiv [Preprint]. 2021 Feb 20:2021.02.20.431155. doi: 10.1101/2021.02.20.431155. bioRxiv. 2021. Update in: Cell. 2021 Sep 2;184(18):4713-4733.e22. doi: 10.1016/j.cell.2021.07.023 PMID: 33619488 Free PMC article. Updated. Preprint.
Small intestinal immunopathology and GI-associated antibody formation in hereditary alpha-tryptasemia.
Konnikova L, Robinson TO, Owings AH, Shirley JF, Davis E, Tang Y, Wall S, Li J, Hasan MH, Gharaibeh RZ, Mendoza Alvarez LB, Ryan LK, Doty A, Chovanec JF, O'Connell MP, Grunes DE, Daley WP, Mayer E, Chang L, Liu J, Snapper SB, Milner JD, Glover SC, Lyons JJ. Konnikova L, et al. Among authors: tang y. J Allergy Clin Immunol. 2021 Sep;148(3):813-821.e7. doi: 10.1016/j.jaci.2021.04.004. Epub 2021 Apr 15. J Allergy Clin Immunol. 2021. PMID: 33865872 Free PMC article.
Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19.
Ziegler CGK, Miao VN, Owings AH, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Christian T, Parker A, Sindel CB, Burger MW, Pride Y, Hasan M, Abraham GE 3rd, Senitko M, Robinson TO, Shalek AK, Glover SC, Horwitz BH, Ordovas-Montanes J. Ziegler CGK, et al. Among authors: tang y. Cell. 2021 Sep 2;184(18):4713-4733.e22. doi: 10.1016/j.cell.2021.07.023. Epub 2021 Jul 23. Cell. 2021. PMID: 34352228 Free PMC article.
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection.
Ziegler CGK, Owings AH, Galeas-Pena M, Kazer SW, Miao VN, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Pride Y, Abraham GE 3rd, Senitko M, Robinson TO, Diamond G, Lionakis MS, Shalek AK, Ordovas-Montanes J, Horwitz BH, Glover SC. Ziegler CGK, et al. Among authors: tang y. Microbiol Spectr. 2024 Jun 4;12(6):e0351623. doi: 10.1128/spectrum.03516-23. Epub 2024 Apr 30. Microbiol Spectr. 2024. PMID: 38687064 Free PMC article.
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