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Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity.
Chen X, Momin A, Wanggou S, Wang X, Min HK, Dou W, Gong Z, Chan J, Dong W, Fan JJ, Xiong Y, Talipova K, Zhao H, Chen YX, Veerasammy K, Fekete A, Kumar SA, Liu H, Yang Q, Son JE, Dou Z, Hu M, Pardis P, Juraschka K, Donovan LK, Zhang J, Ramaswamy V, Selvadurai HJ, Dirks PB, Taylor MD, Wang LY, Hui CC, Abzalimov R, He Y, Sun Y, Li X, Huang X. Chen X, et al. Among authors: fan jj. Neuron. 2023 Jan 4;111(1):30-48.e14. doi: 10.1016/j.neuron.2022.10.007. Epub 2022 Nov 1. Neuron. 2023. PMID: 36323321 Free article.
A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression.
Chen X, Wanggou S, Bodalia A, Zhu M, Dong W, Fan JJ, Yin WC, Min HK, Hu M, Draghici D, Dou W, Li F, Coutinho FJ, Whetstone H, Kushida MM, Dirks PB, Song Y, Hui CC, Sun Y, Wang LY, Li X, Huang X. Chen X, et al. Among authors: fan jj. Neuron. 2018 Nov 21;100(4):799-815.e7. doi: 10.1016/j.neuron.2018.09.046. Epub 2018 Oct 18. Neuron. 2018. PMID: 30344046 Free article.
Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth.
Francisco MA, Wanggou S, Fan JJ, Dong W, Chen X, Momin A, Abeysundara N, Min HK, Chan J, McAdam R, Sia M, Pusong RJ, Liu S, Patel N, Ramaswamy V, Kijima N, Wang LY, Song Y, Kafri R, Taylor MD, Li X, Huang X. Francisco MA, et al. Among authors: fan jj. J Exp Med. 2020 May 4;217(5):e20190971. doi: 10.1084/jem.20190971. J Exp Med. 2020. PMID: 32097463 Free PMC article.
A metabolic function of FGFR3-TACC3 gene fusions in cancer.
Frattini V, Pagnotta SM, Tala, Fan JJ, Russo MV, Lee SB, Garofano L, Zhang J, Shi P, Lewis G, Sanson H, Frederick V, Castano AM, Cerulo L, Rolland DCM, Mall R, Mokhtari K, Elenitoba-Johnson KSJ, Sanson M, Huang X, Ceccarelli M, Lasorella A, Iavarone A. Frattini V, et al. Among authors: fan jj. Nature. 2018 Jan 11;553(7687):222-227. doi: 10.1038/nature25171. Epub 2018 Jan 3. Nature. 2018. PMID: 29323298 Free PMC article.
Super-Enhancer-Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T-ALL Cell Growth and Survival.
Yu J, Zhang Z, Chen Y, Wang J, Li G, Tao Y, Zhang Y, Yang Y, Zhang C, Li T, Cheng J, Ji T, Wei Z, Wang W, Fang F, Jiang W, Chu P, Yin H, Wu D, Li X, Wang X, Fan JJ, Hu S, Zhu ZH, Wu S, Lu J, Pan J. Yu J, et al. Among authors: fan jj. Adv Sci (Weinh). 2025 Jan;12(1):e2407113. doi: 10.1002/advs.202407113. Epub 2024 Oct 25. Adv Sci (Weinh). 2025. PMID: 39454110 Free PMC article.
Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia.
Ji T, Yang Y, Yu J, Yin H, Chu X, Yang P, Xu L, Wang X, Hu S, Li Y, Wu X, Liu W, Zhou B, Wang W, Zhang S, Cheng W, Chen Y, Shi L, Li Z, Zhuo R, Zhang Y, Tao Y, Wu D, Li X, Zhang Z, Fan JJ, Pan J, Lu J. Ji T, et al. Among authors: fan jj. J Exp Clin Cancer Res. 2024 Jul 24;43(1):205. doi: 10.1186/s13046-024-03130-8. J Exp Clin Cancer Res. 2024. PMID: 39044280 Free PMC article.
154 results