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Page 1
Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance.
Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, Neel BG, Andrews ZB, Cowley MA, Tiganis T. Loh K, et al. Among authors: tiganis t. Cell Metab. 2022 Nov 1;34(11):1892. doi: 10.1016/j.cmet.2022.09.010. Cell Metab. 2022. PMID: 36323237 Free PMC article. No abstract available.
miR-33 deletion in hepatocytes attenuates MASLD-MASH-HCC progression.
Fernández-Tussy P, Cardelo MP, Zhang H, Sun J, Price NL, Boutagy NE, Goedeke L, Cadena-Sandoval M, Xirouchaki CE, Brown W, Yang X, Pastor-Rojo O, Haeusler RA, Bennett AM, Tiganis T, Suárez Y, Fernández-Hernando C. Fernández-Tussy P, et al. Among authors: tiganis t. JCI Insight. 2024 Aug 27;9(19):e168476. doi: 10.1172/jci.insight.168476. JCI Insight. 2024. PMID: 39190492 Free PMC article.
MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention.
Qiu B, Lawan A, Xirouchaki CE, Yi JS, Robert M, Zhang L, Brown W, Fernández-Hernando C, Yang X, Tiganis T, Bennett AM. Qiu B, et al. Among authors: tiganis t. bioRxiv [Preprint]. 2023 Jul 11:2023.07.10.548263. doi: 10.1101/2023.07.10.548263. bioRxiv. 2023. Update in: Nat Commun. 2023 Sep 5;14(1):5405. doi: 10.1038/s41467-023-41145-5 PMID: 37502892 Free PMC article. Updated. Preprint.
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Liang S, Tran E, Du X, Dong J, Sudholz H, Chen H, Qu Z, Huntington ND, Babon JJ, Kershaw NJ, Zhang ZY, Baell JB, Wiede F, Tiganis T. Liang S, et al. Among authors: tiganis t. Nat Commun. 2023 Jul 27;14(1):4524. doi: 10.1038/s41467-023-40170-8. Nat Commun. 2023. PMID: 37500611 Free PMC article.
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Liang S, Tran E, Du X, Dong J, Sudholz H, Chen H, Qu Z, Huntington N, Babon J, Kershaw N, Zhang ZY, Baell J, Wiede F, Tiganis T. Liang S, et al. Among authors: tiganis t. bioRxiv [Preprint]. 2023 Jun 28:2023.06.16.545220. doi: 10.1101/2023.06.16.545220. bioRxiv. 2023. Update in: Nat Commun. 2023 Jul 27;14(1):4524. doi: 10.1038/s41467-023-40170-8 PMID: 37397992 Free PMC article. Updated. Preprint.
125 results