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Targeting myeloid suppressive cells revives cytotoxic anti-tumor responses in pancreatic cancer.
Sarhan D, Eisinger S, He F, Bergsland M, Pelicano C, Driescher C, Westberg K, Benitez II, Humoud R, Palano G, Li S, Carannante V, Muhr J, Önfelt B, Schlisio S, Ravetch JV, Heuchel R, Löhr MJ, Karlsson MCI. Sarhan D, et al. Among authors: heuchel r. iScience. 2022 Oct 9;25(11):105317. doi: 10.1016/j.isci.2022.105317. eCollection 2022 Nov 18. iScience. 2022. PMID: 36310582 Free PMC article.
An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver.
Fernández Moro C, Geyer N, Harrizi S, Hamidi Y, Söderqvist S, Kuznyecov D, Tidholm Qvist E, Salmonson Schaad M, Hermann L, Lindberg A, Heuchel RL, Martín-Bernabé A, Dhanjal S, Navis AC, Villard C, Del Valle AC, Bozóky L, Sparrelid E, Dirix L, Strell C, Östman A, Schmierer B, Vermeulen PB, Engstrand J, Bozóky B, Gerling M. Fernández Moro C, et al. Among authors: heuchel rl. Nat Commun. 2023 Aug 18;14(1):5024. doi: 10.1038/s41467-023-40688-x. Nat Commun. 2023. PMID: 37596278 Free PMC article.
FPR2 Shapes an Immune-Excluded Pancreatic Tumor Microenvironment and Drives T-cell Exhaustion in a Sex-Dependent Manner.
He F, Tay AHM, Calandigary A, Malki E, Suzuki S, Liu T, Wang Q, Fernández-Moro C, Kaisso M, Olofsson-Sahl P, Melssen M, Sze SK, Björnstedt M, Löhr MJ, Karlsson MCI, Heuchel R, Sarhan D. He F, et al. Among authors: heuchel r. Cancer Res. 2023 May 15;83(10):1628-1645. doi: 10.1158/0008-5472.CAN-22-2932. Cancer Res. 2023. PMID: 36919330
80 results