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Darobactins Exhibiting Superior Antibiotic Activity by Cryo-EM Structure Guided Biosynthetic Engineering.
Seyfert CE, Porten C, Yuan B, Deckarm S, Panter F, Bader CD, Coetzee J, Deschner F, Tehrani KHME, Higgins PG, Seifert H, Marlovits TC, Herrmann J, Müller R. Seyfert CE, et al. Among authors: porten c. Angew Chem Int Ed Engl. 2023 Jan 9;62(2):e202214094. doi: 10.1002/anie.202214094. Epub 2022 Dec 7. Angew Chem Int Ed Engl. 2023. PMID: 36308277 Free PMC article.
In Vivo Activity Profiling of Biosynthetic Darobactin D22 against Critical Gram-Negative Pathogens.
Kany AM, Fries F, Seyfert CE, Porten C, Deckarm S, Chacón Ortiz M, Dubarry N, Vaddi S, Große M, Bernecker S, Sandargo B, Müller AV, Bacqué E, Stadler M, Herrmann J, Müller R. Kany AM, et al. Among authors: porten c. ACS Infect Dis. 2024 Dec 13;10(12):4337-4346. doi: 10.1021/acsinfecdis.4c00687. Epub 2024 Nov 20. ACS Infect Dis. 2024. PMID: 39565008 Free PMC article.