Li TY - Search Results

1

Design of fast-onset antidepressant by dissociating SERT from nNOS in the DRN.

Sun N, Qin YJ, Xu C, Xia T, Du ZW, Zheng LP, Li AA, Meng F, Zhang Y, Zhang J, Liu X, Li TY, Zhu DY, Zhou QG. Sun N, et al. Among authors: li aa, li ty. Science. 2022 Oct 28;378(6618):390-398. doi: 10.1126/science.abo3566. Epub 2022 Oct 27. Science. 2022. PMID: 36302033

2

Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine.

Imam MZ, Kuo A, Ghassabian S, Cai Y, Qin Y, Li T, Smith MT. Imam MZ, et al. Eur J Pharmacol. 2020 Mar 15;871:172918. doi: 10.1016/j.ejphar.2020.172918. Epub 2020 Jan 17. Eur J Pharmacol. 2020. PMID: 31958457

3

Novel µ opioid antagonists derived from the µ opioid agonists endomorphin and [Dmt¹ ]DALDA (H-Dmt-D-Arg-Phe-Lys-NH₂ ).

Shi S, Xu J, Feng L, Fan X, Chen Z, Qin Y, Chung NN, Li T, Schiller PW. Shi S, et al. Chem Biol Drug Des. 2020 Nov;96(5):1305-1314. doi: 10.1111/cbdd.13743. Epub 2020 Aug 2. Chem Biol Drug Des. 2020. PMID: 32526055

4

Neuroprotective Effect of N-Cyclohexylethyl-[A/G]-[D/E]-X-V Peptides on Ischemic Stroke by Blocking nNOS-CAPON Interaction.

Qin Y, Feng L, Fan X, Zheng L, Zhang Y, Chang L, Li T. Qin Y, et al. ACS Chem Neurosci. 2021 Jan 6;12(1):244-255. doi: 10.1021/acschemneuro.0c00739. Epub 2020 Dec 23. ACS Chem Neurosci. 2021. PMID: 33356131

5

Nitric oxide-donating and reactive oxygen species-responsive prochelators based on 8-hydroxyquinoline as anticancer agents.

Zhang Y, Yang J, Meng T, Qin Y, Li T, Fu J, Yin J. Zhang Y, et al. Eur J Med Chem. 2021 Feb 15;212:113153. doi: 10.1016/j.ejmech.2021.113153. Epub 2021 Jan 5. Eur J Med Chem. 2021. PMID: 33453603

6

In Vitro Assessment of the Metabolic Stability of Two Novel Endomorphin-2 Analogs, CYX-5 and CYX-6, in Rat Liver Microsomes.

Imam MZ, Ghassabian S, Kuo A, Cai Y, Qin Y, Li T, Smith MT. Imam MZ, et al. Eur J Drug Metab Pharmacokinet. 2023 Jul;48(4):463-466. doi: 10.1007/s13318-023-00828-6. Epub 2023 May 12. Eur J Drug Metab Pharmacokinet. 2023. PMID: 37171777 No abstract available.

7

Synthesis and Biological Evaluation of Fentanyl Analogues Modified at Phenyl Groups with Alkyls.

Qin Y, Ni L, Shi J, Zhu Z, Shi S, Lam AL, Magiera J, Sekar S, Kuo A, Smith MT, Li T. Qin Y, et al. ACS Chem Neurosci. 2019 Jan 16;10(1):201-208. doi: 10.1021/acschemneuro.8b00363. Epub 2018 Sep 14. ACS Chem Neurosci. 2019. PMID: 30179508

8

CYX-5, a G-protein biassed MOP receptor agonist, DOP receptor antagonist and KOP receptor agonist, evokes constipation but not respiratory depression relative to morphine in rats.

Imam MZ, Kuo A, Ghassabian S, Cai Y, Qin Y, Li T, Smith MT. Imam MZ, et al. Pharmacol Rep. 2023 Jun;75(3):634-646. doi: 10.1007/s43440-023-00446-8. Epub 2023 Jan 13. Pharmacol Rep. 2023. PMID: 36637684 Free PMC article.

9

Enhancing physical fitness using recreational soccer and basketball: A parallel-controlled 8-week study involving overweight and obese individuals, with consideration of sex-related interactions.

Xu Q, Silva RM, Zmijewski P, Li TY, Li JY, Yang L, Clemente FM. Xu Q, et al. Among authors: li ty. Biol Sport. 2025 Jan;42(1):47-58. doi: 10.5114/biolsport.2025.139081. Epub 2024 May 24. Biol Sport. 2025. PMID: 39758168 Free PMC article.

10

Copper-Catalyzed Oxidative Arylation and Hydroxylation of Indolin-2-ones for Direct Construction of Tetrasubstituted Carbon Centers.

Li TY, Xu LL, Wu DQ, Liu JJ, Yang Y, Miao Z, Xu DZ. Li TY, et al. J Org Chem. 2025 Jan 2. doi: 10.1021/acs.joc.4c01364. Online ahead of print. J Org Chem. 2025. PMID: 39746028

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