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Page 1
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.
Fulton SL, Wenderski W, Lepack AE, Eagle AL, Fanutza T, Bastle RM, Ramakrishnan A, Hays EC, Neal A, Bendl J, Farrelly LA, Al-Kachak A, Lyu Y, Cetin B, Chan JC, Tran TN, Neve RL, Roper RJ, Brennand KJ, Roussos P, Schimenti JC, Friedman AK, Shen L, Blitzer RD, Robison AJ, Crabtree GR, Maze I. Fulton SL, et al. Among authors: al kachak a. Nat Commun. 2022 Oct 26;13(1):6384. doi: 10.1038/s41467-022-34200-0. Nat Commun. 2022. PMID: 36289231 Free PMC article.
Histone serotonylation in dorsal raphe nucleus contributes to stress- and antidepressant-mediated gene expression and behavior.
Al-Kachak A, Di Salvo G, Fulton SL, Chan JC, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Safovich P, Lyu Y, Covington HE 3rd, Shen L, Gleason K, Tamminga CA, Russo SJ, Maze I. Al-Kachak A, et al. Nat Commun. 2024 Jun 13;15(1):5042. doi: 10.1038/s41467-024-49336-4. Nat Commun. 2024. PMID: 38871707 Free PMC article.
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior.
Al-Kachak A, Fulton SL, Di Salvo G, Chan JC, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Safovich P, Lyu Y, Covington HE 3rd, Shen L, Gleason K, Tamminga CA, Russo SJ, Maze I. Al-Kachak A, et al. bioRxiv [Preprint]. 2023 Sep 16:2023.05.04.539464. doi: 10.1101/2023.05.04.539464. bioRxiv. 2023. Update in: Nat Commun. 2024 Jun 13;15(1):5042. doi: 10.1038/s41467-024-49336-4 PMID: 37205414 Free PMC article. Updated. Preprint.
ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex.
Fulton SL, Bendl J, Gameiro-Ros I, Fullard JF, Al-Kachak A, Lepack AE, Stewart AF, Singh S, Poller WC, Bastle RM, Hauberg ME, Fakira AK, Chen M, Cuttoli RD, Cathomas F, Ramakrishnan A, Gleason K, Shen L, Tamminga CA, Milosevic A, Russo SJ, Swirski F, Blitzer RD, Slesinger PA, Roussos P, Maze I. Fulton SL, et al. Among authors: al kachak a. bioRxiv [Preprint]. 2023 May 4:2023.05.04.539425. doi: 10.1101/2023.05.04.539425. bioRxiv. 2023. PMID: 37205394 Free PMC article. Preprint.
Flexible and site-specific manipulation of histones in live animals.
Finkin-Groner E, Al-Kachak A, Agustinus A, Bastle R, Lepack A, Lyu Y, Maze I, David Y. Finkin-Groner E, et al. Among authors: al kachak a. bioRxiv [Preprint]. 2023 Mar 20:2023.03.19.533378. doi: 10.1101/2023.03.19.533378. bioRxiv. 2023. PMID: 36993231 Free PMC article. Preprint.
CREST in the Nucleus Accumbens Core Regulates Cocaine Conditioned Place Preference, Cocaine-Seeking Behavior, and Synaptic Plasticity.
Alaghband Y, Kramár E, Kwapis JL, Kim ES, Hemstedt TJ, López AJ, White AO, Al-Kachak A, Aimiuwu OV, Bodinayake KK, Oparaugo NC, Han J, Lattal KM, Wood MA. Alaghband Y, et al. Among authors: al kachak a. J Neurosci. 2018 Oct 31;38(44):9514-9526. doi: 10.1523/JNEUROSCI.2911-17.2018. Epub 2018 Sep 18. J Neurosci. 2018. PMID: 30228227 Free PMC article.
Distinct roles for the deacetylase domain of HDAC3 in the hippocampus and medial prefrontal cortex in the formation and extinction of memory.
Alaghband Y, Kwapis JL, López AJ, White AO, Aimiuwu OV, Al-Kachak A, Bodinayake KK, Oparaugo NC, Dang R, Astarabadi M, Matheos DP, Wood MA. Alaghband Y, et al. Among authors: al kachak a. Neurobiol Learn Mem. 2017 Nov;145:94-104. doi: 10.1016/j.nlm.2017.09.001. Epub 2017 Sep 8. Neurobiol Learn Mem. 2017. PMID: 28890149 Free PMC article.