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Page 1
Neuroinflammation Plays a Critical Role in Cerebral Cavernous Malformation Disease.
Lai CC, Nelsen B, Frias-Anaya E, Gallego-Gutierrez H, Orecchioni M, Herrera V, Ortiz E, Sun H, Mesarwi OA, Ley K, Gongol B, Lopez-Ramirez MA. Lai CC, et al. Among authors: lopez ramirez ma. Circ Res. 2022 Nov 11;131(11):909-925. doi: 10.1161/CIRCRESAHA.122.321129. Epub 2022 Oct 26. Circ Res. 2022. PMID: 36285625 Free PMC article.
Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations.
Lopez-Ramirez MA, Fonseca G, Zeineddine HA, Girard R, Moore T, Pham A, Cao Y, Shenkar R, de Kreuk BJ, Lagarrigue F, Lawler J, Glass CK, Awad IA, Ginsberg MH. Lopez-Ramirez MA, et al. J Exp Med. 2017 Nov 6;214(11):3331-3346. doi: 10.1084/jem.20171178. Epub 2017 Sep 28. J Exp Med. 2017. PMID: 28970240 Free PMC article.
Phenotypic characterization of murine models of cerebral cavernous malformations.
Zeineddine HA, Girard R, Saadat L, Shen L, Lightle R, Moore T, Cao Y, Hobson N, Shenkar R, Avner K, Chaudager K, Koskimäki J, Polster SP, Fam MD, Shi C, Lopez-Ramirez MA, Tang AT, Gallione C, Kahn ML, Ginsberg M, Marchuk DA, Awad IA. Zeineddine HA, et al. Lab Invest. 2019 Mar;99(3):319-330. doi: 10.1038/s41374-018-0030-y. Epub 2018 Jun 26. Lab Invest. 2019. PMID: 29946133 Free PMC article.
Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.
Lopez-Ramirez MA, Pham A, Girard R, Wyseure T, Hale P, Yamashita A, Koskimäki J, Polster S, Saadat L, Romero IA, Esmon CT, Lagarrigue F, Awad IA, Mosnier LO, Ginsberg MH. Lopez-Ramirez MA, et al. Blood. 2019 Jan 17;133(3):193-204. doi: 10.1182/blood-2018-06-856062. Epub 2018 Nov 15. Blood. 2019. PMID: 30442679 Free PMC article.
Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.
Koskimäki J, Zhang D, Li Y, Saadat L, Moore T, Lightle R, Polster SP, Carrión-Penagos J, Lyne SB, Zeineddine HA, Shi C, Shenkar R, Romanos S, Avner K, Srinath A, Shen L, Detter MR, Snellings D, Cao Y, Lopez-Ramirez MA, Fonseca G, Tang AT, Faber P, Andrade J, Ginsberg M, Kahn ML, Marchuk DA, Girard R, Awad IA. Koskimäki J, et al. Acta Neuropathol Commun. 2019 Aug 19;7(1):132. doi: 10.1186/s40478-019-0789-0. Acta Neuropathol Commun. 2019. PMID: 31426861 Free PMC article.
Talin-1 is the principal platelet Rap1 effector of integrin activation.
Lagarrigue F, Paul DS, Gingras AR, Valadez AJ, Sun H, Lin J, Cuevas MN, Ablack JN, Lopez-Ramirez MA, Bergmeier W, Ginsberg MH. Lagarrigue F, et al. Blood. 2020 Sep 3;136(10):1180-1190. doi: 10.1182/blood.2020005348. Blood. 2020. PMID: 32518959 Free PMC article.
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