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Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life.
Zhang B, Gollapudi D, Gorman J, O'Dell S, Damron LF, McKee K, Asokan M, Yang ES, Pegu A, Lin BC, Chao CW, Chen X, Gama L, Ivleva VB, Law WH, Liu C, Louder MK, Schmidt SD, Shen CH, Shi W, Stein JA, Seaman MS, McDermott AB, Carlton K, Mascola JR, Kwong PD, Lei QP, Doria-Rose NA. Zhang B, et al. Among authors: stein ja. Sci Rep. 2022 Oct 25;12(1):17876. doi: 10.1038/s41598-022-22435-2. Sci Rep. 2022. PMID: 36284200 Free PMC article.
Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation clinical trial.
Ruckwardt TJ, Morabito KM, Phung E, Crank MC, Costner PJ, Holman LA, Chang LA, Hickman SP, Berkowitz NM, Gordon IJ, Yamshchikov GV, Gaudinski MR, Lin B, Bailer R, Chen M, Ortega-Villa AM, Nguyen T, Kumar A, Schwartz RM, Kueltzo LA, Stein JA, Carlton K, Gall JG, Nason MC, Mascola JR, Chen G, Graham BS; VRC 317 study team. Ruckwardt TJ, et al. Among authors: stein ja. Lancet Respir Med. 2021 Oct;9(10):1111-1120. doi: 10.1016/S2213-2600(21)00098-9. Epub 2021 Apr 14. Lancet Respir Med. 2021. PMID: 33864736 Free PMC article. Clinical Trial.
A proof of concept for structure-based vaccine design targeting RSV in humans.
Crank MC, Ruckwardt TJ, Chen M, Morabito KM, Phung E, Costner PJ, Holman LA, Hickman SP, Berkowitz NM, Gordon IJ, Yamshchikov GV, Gaudinski MR, Kumar A, Chang LA, Moin SM, Hill JP, DiPiazza AT, Schwartz RM, Kueltzo L, Cooper JW, Chen P, Stein JA, Carlton K, Gall JG, Nason MC, Kwong PD, Chen GL, Mascola JR, McLellan JS, Ledgerwood JE, Graham BS; VRC 317 Study Team. Crank MC, et al. Among authors: stein ja. Science. 2019 Aug 2;365(6452):505-509. doi: 10.1126/science.aav9033. Science. 2019. PMID: 31371616 Clinical Trial.
A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial.
Martin JE, Sullivan NJ, Enama ME, Gordon IJ, Roederer M, Koup RA, Bailer RT, Chakrabarti BK, Bailey MA, Gomez PL, Andrews CA, Moodie Z, Gu L, Stein JA, Nabel GJ, Graham BS. Martin JE, et al. Among authors: stein ja. Clin Vaccine Immunol. 2006 Nov;13(11):1267-77. doi: 10.1128/CVI.00162-06. Epub 2006 Sep 20. Clin Vaccine Immunol. 2006. PMID: 16988008 Free PMC article. Clinical Trial.
Biodistribution and toxicological safety of adenovirus type 5 and type 35 vectored vaccines against human immunodeficiency virus-1 (HIV-1), Ebola, or Marburg are similar despite differing adenovirus serotype vector, manufacturer's construct, or gene inserts.
Sheets RL, Stein J, Bailer RT, Koup RA, Andrews C, Nason M, He B, Koo E, Trotter H, Duffy C, Manetz TS, Gomez P. Sheets RL, et al. J Immunotoxicol. 2008 Jul;5(3):315-35. doi: 10.1080/15376510802312464. J Immunotoxicol. 2008. PMID: 18830892 Free PMC article.
SpotCheck: A skin cancer diagnostic accuracy study comparing teledermoscopy with and without electrical impedance spectroscopy to in-person dermatologist evaluation of patient-identified lesions concerning them for skin cancer.
Ingrassia JP, Bajaj S, Kolla A, Li V, Shah P, Gulati N, Criscito MC, Xing Y, Lopez A, Tran DC, Ramachandran V, Kakpovbia E, Meehan S, Shao Y, Lo Sicco K, Milam EC, Bieber AK, Levine A, Liebman TN, Stein JA, Polsky D. Ingrassia JP, et al. Among authors: stein ja. J Am Acad Dermatol. 2024 Nov 9:S0190-9622(24)03115-3. doi: 10.1016/j.jaad.2024.10.067. Online ahead of print. J Am Acad Dermatol. 2024. PMID: 39528165 No abstract available.
Lessons learned from the Dermoscopy Bowl for dermatology residents.
Buchanan KL, Liopyris K, Nelson KC, Stein JA, Dusza SW, Ruiz de Luzuriaga A, Seiverling EV. Buchanan KL, et al. Among authors: stein ja. Arch Dermatol Res. 2024 Sep 26;316(9):643. doi: 10.1007/s00403-024-03400-7. Arch Dermatol Res. 2024. PMID: 39325208 Free PMC article. No abstract available.
360 results