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A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.
Jang JY, Hwang I, Pan H, Yao J, Alinari L, Imada E, Zanettini C, Kluk MJ, Wang Y, Lee Y, Lin HV, Huang X, Di Liberto M, Chen Z, Ballman KV, Cantley LC, Marchionni L, Inghirami G, Elemento O, Baiocchi RA, Chen-Kiang S, Belvedere S, Zheng H, Paik J. Jang JY, et al. Among authors: pan h. J Clin Invest. 2022 Dec 15;132(24):e160767. doi: 10.1172/JCI160767. J Clin Invest. 2022. PMID: 36282572 Free PMC article.
Epigenomic evolution in diffuse large B-cell lymphomas.
Pan H, Jiang Y, Boi M, Tabbò F, Redmond D, Nie K, Ladetto M, Chiappella A, Cerchietti L, Shaknovich R, Melnick AM, Inghirami GG, Tam W, Elemento O. Pan H, et al. Nat Commun. 2015 Apr 20;6:6921. doi: 10.1038/ncomms7921. Nat Commun. 2015. PMID: 25891015 Free PMC article.
Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.
Boi M, Todaro M, Vurchio V, Yang SN, Moon J, Kwee I, Rinaldi A, Pan H, Crescenzo R, Cheng M, Cerchietti L, Elemento O, Riveiro ME, Cvitkovic E, Bertoni F, Inghirami G; AIRC 5xMille Consortium ‘Genetics-Driven Targeted Management of Lymphoid Malignancies’. Boi M, et al. Among authors: pan h. Oncotarget. 2016 Nov 29;7(48):79637-79653. doi: 10.18632/oncotarget.12876. Oncotarget. 2016. PMID: 27793034 Free PMC article.
Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy.
Dalton T, Doubrovina E, Pankov D, Reynolds R, Scholze H, Selvakumar A, Vizconde T, Savalia B, Dyomin V, Weigel C, Oakes CC, Alonso A, Elemento O, Pan H, Phillip JM, O'Reilly RJ, Gewurz BE, Cesarman E, Giulino-Roth L. Dalton T, et al. Among authors: pan h. Blood. 2020 May 21;135(21):1870-1881. doi: 10.1182/blood.2019004126. Blood. 2020. PMID: 32157281 Free PMC article.
CIC is a critical regulator of neuronal differentiation.
Hwang I, Pan H, Yao J, Elemento O, Zheng H, Paik J. Hwang I, et al. Among authors: pan h. JCI Insight. 2020 May 7;5(9):e135826. doi: 10.1172/jci.insight.135826. JCI Insight. 2020. PMID: 32229723 Free PMC article.
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