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261 results

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CSL112 (Apolipoprotein A-I [Human]) Strongly Enhances Plasma Apoa-I and Cholesterol Efflux Capacity in Post-Acute Myocardial Infarction Patients: A PK/PD Substudy of the AEGIS-I Trial.
Gibson CM, Kazmi SHA, Korjian S, Chi G, Phillips AT, Montazerin SM, Duffy D, Zheng B, Heise M, Liss C, Deckelbaum LI, Wright SD, Gille A. Gibson CM, et al. Among authors: wright sd. J Cardiovasc Pharmacol Ther. 2022 Jan-Dec;27:10742484221121507. doi: 10.1177/10742484221121507. J Cardiovasc Pharmacol Ther. 2022. PMID: 36282079 Free article. Clinical Trial.
Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial.
Tricoci P, D'Andrea DM, Gurbel PA, Yao Z, Cuchel M, Winston B, Schott R, Weiss R, Blazing MA, Cannon L, Bailey A, Angiolillo DJ, Gille A, Shear CL, Wright SD, Alexander JH. Tricoci P, et al. Among authors: wright sd. J Am Heart Assoc. 2015 Aug 25;4(8):e002171. doi: 10.1161/JAHA.115.002171. J Am Heart Assoc. 2015. PMID: 26307570 Free PMC article. Clinical Trial.
Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component.
Herzog E, Pragst I, Waelchli M, Gille A, Schenk S, Mueller-Cohrs J, Diditchenko S, Zanoni P, Cuchel M, Seubert A, Rader DJ, Wright SD. Herzog E, et al. Among authors: wright sd. J Appl Toxicol. 2016 Aug;36(8):1038-47. doi: 10.1002/jat.3264. Epub 2015 Dec 9. J Appl Toxicol. 2016. PMID: 26651060
Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112: Effects on Cholesterol Efflux, Anti-Inflammatory and Antioxidative Activity.
Didichenko SA, Navdaev AV, Cukier AM, Gille A, Schuetz P, Spycher MO, Thérond P, Chapman MJ, Kontush A, Wright SD. Didichenko SA, et al. Among authors: wright sd. Circ Res. 2016 Sep 2;119(6):751-63. doi: 10.1161/CIRCRESAHA.116.308685. Epub 2016 Jul 19. Circ Res. 2016. PMID: 27436846 Free PMC article. Clinical Trial.
261 results