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Large 22q13.3 deletions perturb peripheral transcriptomic and metabolomic profiles in Phelan-McDermid syndrome.
Breen MS, Fan X, Levy T, Pollak RM, Collins B, Osman A, Tocheva AS, Sahin M, Berry-Kravis E, Soorya L, Thurm A, Powell CM, Bernstein JA, Kolevzon A, Buxbaum JD; Developmental Synaptopathies Consortium. Breen MS, et al. Among authors: osman a. HGG Adv. 2022 Sep 26;4(1):100145. doi: 10.1016/j.xhgg.2022.100145. eCollection 2023 Jan 12. HGG Adv. 2022. PMID: 36276299 Free PMC article.
Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice.
Osman A, Mervosh NL, Strat AN, Euston TJ, Zipursky G, Pollak RM, Meckel KR, Tyler SR, Chan KL, Buxbaum Grice A, Drapeau E, Litichevskiy L, Gill J, Zeldin SM, Thaiss CA, Buxbaum JD, Breen MS, Kiraly DD. Osman A, et al. Brain Behav Immun. 2023 Nov;114:311-324. doi: 10.1016/j.bbi.2023.08.020. Epub 2023 Aug 30. Brain Behav Immun. 2023. PMID: 37657643 Free PMC article.
Stress-activated brain-gut circuits disrupt intestinal barrier integrity and social behaviour.
Russo S, Chan K, Li L, Parise L, Cathomas F, LeClair K, Shimo Y, Lin HY, Durand-de Cuttoli R, Aubry A, Alvarez J, Drescher T, Osman A, Yuan C, Fisher-Foye R, Price G, Schmitt Y, Kaster M, Furtado GC, Lira S, Wang J, Han W, de Araujo I. Russo S, et al. Among authors: osman a. Res Sq [Preprint]. 2023 Oct 27:rs.3.rs-3459170. doi: 10.21203/rs.3.rs-3459170/v1. Res Sq. 2023. PMID: 37961128 Free PMC article. Preprint.
Ad-derived bone marrow transplant induces proinflammatory immune peripheral mechanisms accompanied by decreased neuroplasticity and reduced gut microbiome diversity affecting AD-like phenotype in the absence of Aβ neuropathology.
Iban-Arias R, Yang EJ, Griggs E, Soares Dias Portela A, Osman A, Trageser KJ, Shahed M, Maria Pasinetti G. Iban-Arias R, et al. Among authors: osman a. Brain Behav Immun. 2024 May;118:252-272. doi: 10.1016/j.bbi.2024.03.012. Epub 2024 Mar 8. Brain Behav Immun. 2024. PMID: 38461954
1,879 results