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130 results

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Favipiravir, lopinavir-ritonavir, or combination therapy (FLARE): A randomised, double-blind, 2 × 2 factorial placebo-controlled trial of early antiviral therapy in COVID-19.
Lowe DM, Brown LK, Chowdhury K, Davey S, Yee P, Ikeji F, Ndoutoumou A, Shah D, Lennon A, Rai A, Agyeman AA, Checkley A, Longley N, Dehbi HM, Freemantle N, Breuer J, Standing JF; FLARE Investigators. Lowe DM, et al. PLoS Med. 2022 Oct 19;19(10):e1004120. doi: 10.1371/journal.pmed.1004120. eCollection 2022 Oct. PLoS Med. 2022. PMID: 36260627 Free PMC article. Clinical Trial.
Norovirus infection in primary immune deficiency.
Brown LK, Clark I, Brown JR, Breuer J, Lowe DM. Brown LK, et al. Among authors: lowe dm. Rev Med Virol. 2017 May;27(3):e1926. doi: 10.1002/rmv.1926. Epub 2017 Mar 8. Rev Med Virol. 2017. PMID: 28271593 Review.
Mutagenesis in Norovirus in Response to Favipiravir Treatment.
Ruis C, Brown LK, Roy S, Atkinson C, Williams R, Burns SO, Yara-Romero E, Jacobs M, Goldstein R, Breuer J, Lowe DM. Ruis C, et al. Among authors: lowe dm. N Engl J Med. 2018 Nov 29;379(22):2173-2176. doi: 10.1056/NEJMc1806941. N Engl J Med. 2018. PMID: 30485769 Free article. No abstract available.
Viral infection in primary antibody deficiency syndromes.
Jones TPW, Buckland M, Breuer J, Lowe DM. Jones TPW, et al. Among authors: lowe dm. Rev Med Virol. 2019 Jul;29(4):e2049. doi: 10.1002/rmv.2049. Epub 2019 Apr 24. Rev Med Virol. 2019. PMID: 31016825 Review.
A comprehensive characterization of chronic norovirus infection in immunodeficient hosts.
Brown LK, Ruis C, Clark I, Roy S, Brown JR, Albuquerque AS, Patel SY, Miller J, Karim MY, Dervisevic S, Moore J, Williams CA, Cudini J, Moreira F, Neild P, Seneviratne SL, Workman S, Toumpanakis C, Atkinson C, Burns SO, Breuer J, Lowe DM. Brown LK, et al. Among authors: lowe dm. J Allergy Clin Immunol. 2019 Nov;144(5):1450-1453. doi: 10.1016/j.jaci.2019.07.036. Epub 2019 Aug 13. J Allergy Clin Immunol. 2019. PMID: 31415785 Free PMC article. No abstract available.
Early phase dose-finding trials in virology.
Dehbi HM, Lowe DM, O'Quigley J. Dehbi HM, et al. Among authors: lowe dm. Stat Med. 2021 Jan 30;40(2):240-253. doi: 10.1002/sim.8771. Epub 2020 Oct 14. Stat Med. 2021. PMID: 33053601
Treatment of chronic or relapsing COVID-19 in immunodeficiency.
Brown LK, Moran E, Goodman A, Baxendale H, Bermingham W, Buckland M, AbdulKhaliq I, Jarvis H, Hunter M, Karanam S, Patel A, Jenkins M, Robbins A, Khan S, Simpson T, Jolles S, Underwood J, Savic S, Richter A, Shields A, Brown M, Lowe DM. Brown LK, et al. Among authors: lowe dm. J Allergy Clin Immunol. 2022 Feb;149(2):557-561.e1. doi: 10.1016/j.jaci.2021.10.031. Epub 2021 Nov 12. J Allergy Clin Immunol. 2022. PMID: 34780850 Free PMC article.
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Butler CC, Hobbs FDR, Gbinigie OA, Rahman NM, Hayward G, Richards DB, Dorward J, Lowe DM, Standing JF, Breuer J, Khoo S, Petrou S, Hood K, Nguyen-Van-Tam JS, Patel MG, Saville BR, Marion J, Ogburn E, Allen J, Rutter H, Francis N, Thomas NPB, Evans P, Dobson M, Madden TA, Holmes J, Harris V, Png ME, Lown M, van Hecke O, Detry MA, Saunders CT, Fitzgerald M, Berry NS, Mwandigha L, Galal U, Mort S, Jani BD, Hart ND, Ahmed H, Butler D, McKenna M, Chalk J, Lavallee L, Hadley E, Cureton L, Benysek M, Andersson M, Coates M, Barrett S, Bateman C, Davies JC, Raymundo-Wood I, Ustianowski A, Carson-Stevens A, Yu LM, Little P; PANORAMIC Trial Collaborative Group. Butler CC, et al. Among authors: lowe dm. Lancet. 2023 Jan 28;401(10373):281-293. doi: 10.1016/S0140-6736(22)02597-1. Epub 2022 Dec 22. Lancet. 2023. PMID: 36566761 Free PMC article. Clinical Trial.
130 results