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Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis.
Edavettal S, Cejudo-Martin P, Dasgupta B, Yang D, Buschman MD, Domingo D, Van Kolen K, Jaiprasat P, Gordon R, Schutsky K, Geist B, Taylor N, Soubrane CH, Van Der Helm E, LaCombe A, Ainekulu Z, Lacy E, Aligo J, Ho J, He Y, Lebowitz PF, Patterson JT, Scheer JM, Singh S. Edavettal S, et al. Among authors: singh s. Med. 2022 Dec 9;3(12):860-882.e15. doi: 10.1016/j.medj.2022.09.007. Epub 2022 Oct 17. Med. 2022. PMID: 36257298 Free article.
IgG Charge: Practical and Biological Implications.
Yang D, Kroe-Barrett R, Singh S, Laue T. Yang D, et al. Among authors: singh s. Antibodies (Basel). 2019 Mar 14;8(1):24. doi: 10.3390/antib8010024. Antibodies (Basel). 2019. PMID: 31544830 Free PMC article.
Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn.
Yang D, Giragossian C, Castellano S, Lasaro M, Xiao H, Saraf H, Hess Kenny C, Rybina I, Huang ZF, Ahlberg J, Bigwarfe T, Myzithras M, Waltz E, Roberts S, Kroe-Barrett R, Singh S. Yang D, et al. Among authors: singh s. MAbs. 2017 Oct;9(7):1105-1117. doi: 10.1080/19420862.2017.1359455. Epub 2017 Aug 8. MAbs. 2017. PMID: 28786732 Free PMC article.
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