Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

117 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.
Rumpf T, Schiedel M, Karaman B, Roessler C, North BJ, Lehotzky A, Oláh J, Ladwein KI, Schmidtkunz K, Gajer M, Pannek M, Steegborn C, Sinclair DA, Gerhardt S, Ovádi J, Schutkowski M, Sippl W, Einsle O, Jung M. Rumpf T, et al. Among authors: schutkowski m. Nat Commun. 2015 Feb 12;6:6263. doi: 10.1038/ncomms7263. Nat Commun. 2015. PMID: 25672491 Free PMC article.
Histone Deacetylase 11 Is a Fatty-Acid Deacylase.
Kutil Z, Novakova Z, Meleshin M, Mikesova J, Schutkowski M, Barinka C. Kutil Z, et al. Among authors: schutkowski m. ACS Chem Biol. 2018 Mar 16;13(3):685-693. doi: 10.1021/acschembio.7b00942. Epub 2018 Jan 30. ACS Chem Biol. 2018. PMID: 29336543
Potent and Selective Inhibitors of Human Sirtuin 5.
Kalbas D, Liebscher S, Nowak T, Meleshin M, Pannek M, Popp C, Alhalabi Z, Bordusa F, Sippl W, Steegborn C, Schutkowski M. Kalbas D, et al. Among authors: schutkowski m. J Med Chem. 2018 Mar 22;61(6):2460-2471. doi: 10.1021/acs.jmedchem.7b01648. Epub 2018 Mar 12. J Med Chem. 2018. PMID: 29494161
Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors.
Kutil Z, Mikešová J, Zessin M, Meleshin M, Nováková Z, Alquicer G, Kozikowski A, Sippl W, Bařinka C, Schutkowski M. Kutil Z, et al. Among authors: schutkowski m. ACS Omega. 2019 Nov 15;4(22):19895-19904. doi: 10.1021/acsomega.9b02808. eCollection 2019 Nov 26. ACS Omega. 2019. PMID: 31788622 Free PMC article.
Continuous Sirtuin/HDAC (histone deacetylase) activity assay using thioamides as PET (Photoinduced Electron Transfer)-based fluorescence quencher.
Zessin M, Meleshin M, Simic Z, Kalbas D, Arbach M, Gebhardt P, Melesina J, Liebscher S, Bordusa F, Sippl W, Barinka C, Schutkowski M. Zessin M, et al. Among authors: schutkowski m. Bioorg Chem. 2021 Dec;117:105425. doi: 10.1016/j.bioorg.2021.105425. Epub 2021 Oct 12. Bioorg Chem. 2021. PMID: 34695733 Free article.
Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.
Ibrahim HS, Abdelsalam M, Zeyn Y, Zessin M, Mustafa AM, Fischer MA, Zeyen P, Sun P, Bülbül EF, Vecchio A, Erdmann F, Schmidt M, Robaa D, Barinka C, Romier C, Schutkowski M, Krämer OH, Sippl W. Ibrahim HS, et al. Among authors: schutkowski m. Int J Mol Sci. 2021 Dec 29;23(1):369. doi: 10.3390/ijms23010369. Int J Mol Sci. 2021. PMID: 35008795 Free PMC article.
117 results