Shern JF - Search Results

1

Loss of CASZ1 tumor suppressor linked to oncogenic subversion of neuroblastoma core regulatory circuitry.

Liu Z, Zhang X, Xu M, Lei H, Shern JF, Thiele CJ. Liu Z, et al. Among authors: shern jf. Cell Death Dis. 2022 Oct 15;13(10):871. doi: 10.1038/s41419-022-05314-6. Cell Death Dis. 2022. PMID: 36243768 Free PMC article.

2

CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.

Jacoby E, Nguyen SM, Fountaine TJ, Welp K, Gryder B, Qin H, Yang Y, Chien CD, Seif AE, Lei H, Song YK, Khan J, Lee DW, Mackall CL, Gardner RA, Jensen MC, Shern JF, Fry TJ. Jacoby E, et al. Among authors: shern jf. Nat Commun. 2016 Jul 27;7:12320. doi: 10.1038/ncomms12320. Nat Commun. 2016. PMID: 27460500 Free PMC article.

3

KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis.

Murgai M, Ju W, Eason M, Kline J, Beury DW, Kaczanowska S, Miettinen MM, Kruhlak M, Lei H, Shern JF, Cherepanova OA, Owens GK, Kaplan RN. Murgai M, et al. Among authors: shern jf. Nat Med. 2017 Oct;23(10):1176-1190. doi: 10.1038/nm.4400. Epub 2017 Sep 18. Nat Med. 2017. PMID: 28920957 Free PMC article.

4

Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib.

Kraft IL, Akshintala S, Zhu Y, Lei H, Derse-Anthony C, Dombi E, Steinberg SM, Lodish M, Waguespack SG, Kapustina O, Fox E, Balis FM, Merino MJ, Meltzer PS, Glod JW, Shern JF, Widemann BC. Kraft IL, et al. Among authors: shern jf. Clin Cancer Res. 2018 Feb 15;24(4):753-765. doi: 10.1158/1078-0432.CCR-17-2101. Epub 2017 Nov 29. Clin Cancer Res. 2018. PMID: 29187393 Free PMC article.

5

Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes.

Xu L, Zheng Y, Liu J, Rakheja D, Singleterry S, Laetsch TW, Shern JF, Khan J, Triche TJ, Hawkins DS, Amatruda JF, Skapek SX. Xu L, et al. Among authors: shern jf. Cell Rep. 2018 Jul 3;24(1):238-251. doi: 10.1016/j.celrep.2018.06.006. Cell Rep. 2018. PMID: 29972784 Free PMC article.

6

Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence.

Ramakrishna S, Highfill SL, Walsh Z, Nguyen SM, Lei H, Shern JF, Qin H, Kraft IL, Stetler-Stevenson M, Yuan CM, Hwang JD, Feng Y, Zhu Z, Dimitrov D, Shah NN, Fry TJ. Ramakrishna S, et al. Among authors: shern jf. Clin Cancer Res. 2019 Sep 1;25(17):5329-5341. doi: 10.1158/1078-0432.CCR-18-3784. Epub 2019 May 20. Clin Cancer Res. 2019. PMID: 31110075 Free PMC article.

7

Chemical genomics reveals histone deacetylases are required for core regulatory transcription.

Gryder BE, Wu L, Woldemichael GM, Pomella S, Quinn TR, Park PMC, Cleveland A, Stanton BZ, Song Y, Rota R, Wiest O, Yohe ME, Shern JF, Qi J, Khan J. Gryder BE, et al. Among authors: shern jf. Nat Commun. 2019 Jul 8;10(1):3004. doi: 10.1038/s41467-019-11046-7. Nat Commun. 2019. PMID: 31285436 Free PMC article.

8

Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma.

Yeung C, Gibson AE, Issaq SH, Oshima N, Baumgart JT, Edessa LD, Rai G, Urban DJ, Johnson MS, Benavides GA, Squadrito GL, Yohe ME, Lei H, Eldridge S, Hamre J 3rd, Dowdy T, Ruiz-Rodado V, Lita A, Mendoza A, Shern JF, Larion M, Helman LJ, Stott GM, Krishna MC, Hall MD, Darley-Usmar V, Neckers LM, Heske CM. Yeung C, et al. Among authors: shern jf. Cancer Res. 2019 Oct 1;79(19):5060-5073. doi: 10.1158/0008-5472.CAN-19-0217. Epub 2019 Aug 20. Cancer Res. 2019. PMID: 31431459 Free PMC article.

9

Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma.

Gryder BE, Pomella S, Sayers C, Wu XS, Song Y, Chiarella AM, Bagchi S, Chou HC, Sinniah RS, Walton A, Wen X, Rota R, Hathaway NA, Zhao K, Chen J, Vakoc CR, Shern JF, Stanton BZ, Khan J. Gryder BE, et al. Among authors: shern jf. Nat Genet. 2019 Dec;51(12):1714-1722. doi: 10.1038/s41588-019-0534-4. Epub 2019 Nov 29. Nat Genet. 2019. PMID: 31784732 Free PMC article.

10

CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG.

Liu Z, Zhang X, Lei H, Lam N, Carter S, Yockey O, Xu M, Mendoza A, Hernandez ER, Wei JS, Khan J, Yohe ME, Shern JF, Thiele CJ. Liu Z, et al. Among authors: shern jf. Nat Commun. 2020 Feb 14;11(1):911. doi: 10.1038/s41467-020-14684-4. Nat Commun. 2020. PMID: 32060262 Free PMC article.

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