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BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma.
Tamai K, Nakamura-Shima M, Shibuya-Takahashi R, Kanno SI, Yasui A, Mochizuki M, Iwai W, Wakui Y, Abue M, Yamamoto K, Miura K, Mizuma M, Unno M, Kawamura S, Sato I, Yasuda J, Yamaguchi K, Sugamura K, Satoh K. Tamai K, et al. Among authors: iwai w. Sci Rep. 2020 Dec 9;10(1):21592. doi: 10.1038/s41598-020-78539-0. Sci Rep. 2020. PMID: 33299012 Free PMC article.
Discovery of a chemical compound that suppresses expression of BEX2, a dormant cancer stem cell-related protein.
Saijoh S, Nakamura-Shima M, Shibuya-Takahashi R, Ito R, Sugawara A, Yamazaki T, Imai T, Asada Y, Matsuura K, Iwai W, Wakui Y, Abue M, Kawamura S, Katayose Y, Fujimori H, Mochizuki M, Yasuda J, Yamaguchi K, Sugamura K, Satoh K, Katori Y, Tamai K. Saijoh S, et al. Among authors: iwai w. Biochem Biophys Res Commun. 2021 Jan 22;537:132-139. doi: 10.1016/j.bbrc.2020.11.022. Epub 2021 Jan 4. Biochem Biophys Res Commun. 2021. PMID: 33412384
Kyoto classification risk scoring system and endoscopic grading of gastric intestinal metaplasia for gastric cancer: Multicenter observation study in Japan.
Kawamura M, Uedo N, Koike T, Kanesaka T, Hatta W, Ogata Y, Oikawa T, Iwai W, Yokosawa S, Honda J, Asonuma S, Okata H, Ohyauchi M, Ito H, Abe Y, Ara N, Kayaba S, Shinkai H, Shimokawa T. Kawamura M, et al. Among authors: iwai w. Dig Endosc. 2022 Mar;34(3):508-516. doi: 10.1111/den.14114. Epub 2021 Sep 16. Dig Endosc. 2022. PMID: 34415621
BEX2 is required for maintaining dormant cancer stem cell in hepatocellular carcinoma.
Fukushi D, Shibuya-Takahashi R, Mochizuki M, Fujimori H, Kogure T, Sugai T, Iwai W, Wakui Y, Abue M, Murakami K, Nakamura Y, Yasuda J, Yamaguchi K, Sugamura K, Shibata C, Katayose Y, Satoh K, Tamai K. Fukushi D, et al. Among authors: iwai w. Cancer Sci. 2021 Nov;112(11):4580-4592. doi: 10.1111/cas.15115. Epub 2021 Sep 4. Cancer Sci. 2021. PMID: 34424582 Free PMC article.
Combined assessment of clinical and pathological prognostic factors for deciding treatment strategies for esophageal squamous cell carcinoma invading into the muscularis mucosa or submucosa after endoscopic submucosal dissection.
Shimada T, Hatta W, Takahashi S, Koike T, Ohira T, Hikichi T, Toya Y, Tanaka I, Onozato Y, Hamada K, Fukushi D, Watanabe K, Kayaba S, Ito H, Mikami T, Oikawa T, Takahashi Y, Kondo Y, Yoshimura T, Shiroki T, Nagino K, Hanabata N, Funakubo A, Nakamura J, Matsumoto T, Iijima K, Fukuda S, Masamune A, Ito K; Tohoku GI Endoscopy Group. Shimada T, et al. Dig Endosc. 2022 Nov;34(7):1382-1391. doi: 10.1111/den.14378. Epub 2022 Aug 9. Dig Endosc. 2022. PMID: 35702926
Smoking history and severe atrophic gastritis assessed by pepsinogen are risk factors for the prevalence of synchronous gastric cancers in patients with gastric endoscopic submucosal dissection: a multicenter prospective cohort study.
Hatta W, Koike T, Asonuma S, Okata H, Uno K, Oikawa T, Iwai W, Yonechi M, Fukushi D, Kayaba S, Kikuchi R, Ohyauchi M, Fushiya J, Maejima R, Abe Y, Kawamura M, Honda J, Kondo Y, Dairaku N, Norita K, Watanabe K, Takahashi K, Echigo H, Abe Y, Endo H, Okata T, Hoshi T, Nakamura T, Nakaya N, Iijima K, Masamune A; Tohoku G. I. study group. Hatta W, et al. Among authors: iwai w. J Gastroenterol. 2023 May;58(5):433-443. doi: 10.1007/s00535-023-01967-y. Epub 2023 Feb 14. J Gastroenterol. 2023. PMID: 36786863
Blue light imaging and linked color imaging as a screening mode for esophageal squamous cell carcinoma in high-risk patients: Multicenter randomized trial.
Ogata Y, Hatta W, Koike T, Takahashi S, Matsuhashi T, Oikawa T, Iwai W, Asonuma S, Okata H, Ohyauchi M, Ito H, Abe Y, Sasaki Y, Kawamura M, Saito M, Uno K, Fujishima F, Nakamura T, Nakaya N, Iijima K, Masamune A. Ogata Y, et al. Among authors: iwai w. Dig Endosc. 2023 Nov;35(7):835-844. doi: 10.1111/den.14538. Epub 2023 Mar 28. Dig Endosc. 2023. PMID: 36802097 Clinical Trial.
31 results