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Loss-of-function mutations in CEP78 cause male infertility in humans and mice.
Zhang X, Zheng R, Liang C, Liu H, Zhang X, Ma Y, Liu M, Zhang W, Yang Y, Liu M, Jiang C, Ren Q, Wang Y, Chen S, Yang Y, Shen Y. Zhang X, et al. Among authors: yang y. Sci Adv. 2022 Oct 7;8(40):eabn0968. doi: 10.1126/sciadv.abn0968. Epub 2022 Oct 7. Sci Adv. 2022. PMID: 36206347 Free PMC article.
A mutation-independent CRISPR-Cas9-mediated gene targeting approach to treat a murine model of ornithine transcarbamylase deficiency.
Wang L, Yang Y, Breton C, Bell P, Li M, Zhang J, Che Y, Saveliev A, He Z, White J, Latshaw C, Xu C, McMenamin D, Yu H, Morizono H, Batshaw ML, Wilson JM. Wang L, et al. Among authors: yang y. Sci Adv. 2020 Feb 12;6(7):eaax5701. doi: 10.1126/sciadv.aax5701. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32095520 Free PMC article.
circNEIL3 inhibits tumor metastasis through recruiting the E3 ubiquitin ligase Nedd4L to degrade YBX1.
Chen S, Li K, Guo J, Chen HN, Ming Y, Jin Y, Xu F, Zhang T, Yang Y, Ye Z, Liu W, Ma H, Cheng J, Zhou JK, Li Z, Shen S, Dai L, Zhou ZG, Xu H, Peng Y. Chen S, et al. Among authors: yang y. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2215132120. doi: 10.1073/pnas.2215132120. Epub 2023 Mar 24. Proc Natl Acad Sci U S A. 2023. PMID: 36961927 Free PMC article.
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