El-Hamamsy MH - Search Results

1

Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX.

Zain-Alabdeen AI, El-Moselhy TF, Sharafeldin N, Angeli A, Supuran CT, El-Hamamsy MH. Zain-Alabdeen AI, et al. Among authors: el hamamsy mh. Sci Rep. 2022 Oct 6;12(1):16756. doi: 10.1038/s41598-022-21024-7. Sci Rep. 2022. PMID: 36202955 Free PMC article.

2

Design, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors.

El-Hamamsy MH, Sharafeldin NA, El-Moselhy TF, Tawfik HO. El-Hamamsy MH, et al. Arch Pharm (Weinheim). 2020 Aug;353(8):e2000060. doi: 10.1002/ardp.202000060. Epub 2020 May 26. Arch Pharm (Weinheim). 2020. PMID: 32452567

3

Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach.

Tawfik HO, Petreni A, Supuran CT, El-Hamamsy MH. Tawfik HO, et al. Eur J Med Chem. 2022 Mar 15;232:114190. doi: 10.1016/j.ejmech.2022.114190. Epub 2022 Feb 12. Eur J Med Chem. 2022. PMID: 35182815

4

Dependence on linkers' flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents.

Tawfik HO, Belal A, Abourehab MAS, Angeli A, Bonardi A, Supuran CT, El-Hamamsy MH. Tawfik HO, et al. Among authors: el hamamsy mh. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2765-2785. doi: 10.1080/14756366.2022.2130285. J Enzyme Inhib Med Chem. 2022. PMID: 36210545 Free PMC article.

5

Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors.

Tawfik HO, El-Moselhy TF, El-Din NS, El-Hamamsy MH. Tawfik HO, et al. Bioorg Med Chem. 2019 Dec 1;27(23):115126. doi: 10.1016/j.bmc.2019.115126. Epub 2019 Oct 18. Bioorg Med Chem. 2019. PMID: 31648875

6

Discovery of new symmetrical and asymmetrical nitrile-containing 1,4-dihydropyridine derivatives as dual kinases and P-glycoprotein inhibitors: synthesis, in vitro assays, and in silico studies.

Saad MH, El-Moselhy TF, S El-Din N, Mehany ABM, Belal A, Abourehab MAS, Tawfik HO, El-Hamamsy MH. Saad MH, et al. Among authors: el hamamsy mh. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2489-2511. doi: 10.1080/14756366.2022.2120478. J Enzyme Inhib Med Chem. 2022. PMID: 36093880 Free PMC article.

7

Corrigendum to "Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors" [Bioorg. Med. Chem. 27 (2019) 115126].

Tawfik HO, El-Moselhy TF, El-Din NS, El-Hamamsy MH. Tawfik HO, et al. Bioorg Med Chem. 2020 Jan 15;28(2):115255. doi: 10.1016/j.bmc.2019.115255. Epub 2019 Dec 17. Bioorg Med Chem. 2020. PMID: 31862309 No abstract available.

8

Corrigendum to "Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors" [Bioorg. Med. Chem. 27 (2019) 115126].

Tawfik HO, El-Moselhy TF, El-Din NS, El-Hamamsy MH. Tawfik HO, et al. Bioorg Med Chem. 2020 Oct 1;28(19):115687. doi: 10.1016/j.bmc.2020.115687. Epub 2020 Aug 18. Bioorg Med Chem. 2020. PMID: 32826133 No abstract available.

9

Synthesis, Evaluation of Pharmacological Activity, and Molecular Docking of 1,4-Dihydropyridines as Calcium Antagonists.

Shaldam MA, El-Hamamsy MH, Saleh DO, El-Moselhy TF. Shaldam MA, et al. Chem Pharm Bull (Tokyo). 2016;64(4):297-304. doi: 10.1248/cpb.c15-00737. Epub 2016 Jan 27. Chem Pharm Bull (Tokyo). 2016. PMID: 26822207 Free article.

10

New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer.

Tawfik HO, El-Hamaky AA, El-Bastawissy EA, Shcherbakov KA, Veselovsky AV, Gladilina YA, Zhdanov DD, El-Hamamsy MH. Tawfik HO, et al. Among authors: el hamamsy mh. Pharmaceuticals (Basel). 2022 Apr 14;15(4):481. doi: 10.3390/ph15040481. Pharmaceuticals (Basel). 2022. PMID: 35455478 Free PMC article.

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