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Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.
Sasako T, Umehara T, Soeda K, Kaneko K, Suzuki M, Kobayashi N, Okazaki Y, Tamura-Nakano M, Chiba T, Accili D, Kahn CR, Noda T, Asahara H, Yamauchi T, Kadowaki T, Ueki K. Sasako T, et al. Among authors: asahara h. Nat Commun. 2022 Oct 5;13(1):5655. doi: 10.1038/s41467-022-33008-2. Nat Commun. 2022. PMID: 36198696 Free PMC article.
Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway.
Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, Kobayashi M, Iwane A, Sasako T, Okazaki Y, Ohsugi M, Takamoto I, Yamashita S, Asahara H, Akira S, Kasuga M, Kadowaki T. Awazawa M, et al. Among authors: asahara h. Cell Metab. 2011 Apr 6;13(4):401-412. doi: 10.1016/j.cmet.2011.02.010. Cell Metab. 2011. PMID: 21459325 Free article.
Ablation of miR-146b in mice causes hematopoietic malignancy.
Mitsumura T, Ito Y, Chiba T, Matsushima T, Kurimoto R, Tanaka Y, Kato T, Uchida K, Ito T, Yamamoto K, Eishi Y, Kitagawa M, Miyazaki Y, Inase N, Asahara H. Mitsumura T, et al. Among authors: asahara h. Blood Adv. 2018 Dec 11;2(23):3483-3491. doi: 10.1182/bloodadvances.2018017954. Blood Adv. 2018. PMID: 30530754 Free PMC article.
Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.
Sasako T, Ohsugi M, Kubota N, Itoh S, Okazaki Y, Terai A, Kubota T, Yamashita S, Nakatsukasa K, Kamura T, Iwayama K, Tokuyama K, Kiyonari H, Furuta Y, Shibahara J, Fukayama M, Enooku K, Okushin K, Tsutsumi T, Tateishi R, Tobe K, Asahara H, Koike K, Kadowaki T, Ueki K. Sasako T, et al. Among authors: asahara h. Nat Commun. 2019 Feb 27;10(1):947. doi: 10.1038/s41467-019-08591-6. Nat Commun. 2019. PMID: 30814508 Free PMC article.
322 results