Rawlings DJ - Search Results

1

Pancreatic islet-specific engineered T_regs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.

Yang SJ, Singh AK, Drow T, Tappen T, Honaker Y, Barahmand-Pour-Whitman F, Linsley PS, Cerosaletti K, Mauk K, Xiang Y, Smith J, Mortensen E, Cook PJ, Sommer K, Khan I, Liggitt D, Rawlings DJ, Buckner JH. Yang SJ, et al. Among authors: rawlings dj. Sci Transl Med. 2022 Oct 5;14(665):eabn1716. doi: 10.1126/scitranslmed.abn1716. Epub 2022 Oct 5. Sci Transl Med. 2022. PMID: 36197963

2

Phosphorylation of the CARMA1 linker controls NF-kappaB activation.

Sommer K, Guo B, Pomerantz JL, Bandaranayake AD, Moreno-García ME, Ovechkina YL, Rawlings DJ. Sommer K, et al. Among authors: rawlings dj. Immunity. 2005 Dec;23(6):561-74. doi: 10.1016/j.immuni.2005.09.014. Immunity. 2005. PMID: 16356855 Free article.

3

Proximal signals controlling B-cell antigen receptor (BCR) mediated NF-kappaB activation.

Moreno-García ME, Sommer KM, Bandaranayake AD, Rawlings DJ. Moreno-García ME, et al. Among authors: rawlings dj. Adv Exp Med Biol. 2006;584:89-106. doi: 10.1007/0-387-34132-3_7. Adv Exp Med Biol. 2006. PMID: 16802601 Review. No abstract available.

4

The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes.

Rawlings DJ, Sommer K, Moreno-García ME. Rawlings DJ, et al. Nat Rev Immunol. 2006 Nov;6(11):799-812. doi: 10.1038/nri1944. Nat Rev Immunol. 2006. PMID: 17063183 Review.

5

Serine 649 phosphorylation within the protein kinase C-regulated domain down-regulates CARMA1 activity in lymphocytes.

Moreno-García ME, Sommer K, Haftmann C, Sontheimer C, Andrews SF, Rawlings DJ. Moreno-García ME, et al. Among authors: rawlings dj. J Immunol. 2009 Dec 1;183(11):7362-70. doi: 10.4049/jimmunol.0902438. Epub 2009 Nov 16. J Immunol. 2009. PMID: 19917688 Free PMC article.

6

MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity.

Moreno-García ME, Sommer K, Shinohara H, Bandaranayake AD, Kurosaki T, Rawlings DJ. Moreno-García ME, et al. Among authors: rawlings dj. Mol Cell Biol. 2010 Feb;30(4):922-34. doi: 10.1128/MCB.01129-09. Epub 2009 Dec 14. Mol Cell Biol. 2010. PMID: 20008554 Free PMC article.

7

B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia.

Kerns HM, Ryu BY, Stirling BV, Sather BD, Astrakhan A, Humblet-Baron S, Liggitt D, Rawlings DJ. Kerns HM, et al. Among authors: rawlings dj. Blood. 2010 Mar 18;115(11):2146-55. doi: 10.1182/blood-2009-09-241869. Epub 2010 Jan 21. Blood. 2010. PMID: 20093406 Free PMC article.

8

WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.

Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Jackson SW, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Alpers CE, Rawlings DJ. Becker-Herman S, et al. Among authors: rawlings dj. J Exp Med. 2011 Sep 26;208(10):2033-42. doi: 10.1084/jem.20110200. Epub 2011 Aug 29. J Exp Med. 2011. PMID: 21875954 Free PMC article.

9

Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant.

Habib T, Funk A, Rieck M, Brahmandam A, Dai X, Panigrahi AK, Luning Prak ET, Meyer-Bahlburg A, Sanda S, Greenbaum C, Rawlings DJ, Buckner JH. Habib T, et al. Among authors: rawlings dj. J Immunol. 2012 Jan 1;188(1):487-96. doi: 10.4049/jimmunol.1102176. Epub 2011 Nov 21. J Immunol. 2012. PMID: 22105996 Free PMC article. Clinical Trial.

10

Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-κB activation.

Moreno-García ME, Sommer K, Rincon-Arano H, Brault M, Ninomiya-Tsuji J, Matesic LE, Rawlings DJ. Moreno-García ME, et al. Among authors: rawlings dj. Mol Cell Biol. 2013 Mar;33(6):1149-63. doi: 10.1128/MCB.06407-11. Epub 2013 Jan 7. Mol Cell Biol. 2013. PMID: 23297344 Free PMC article.

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