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Zebrafish modeling of intestinal injury, bacterial exposures and medications defines epithelial in vivo responses relevant to human inflammatory bowel disease.
Chuang LS, Morrison J, Hsu NY, Labrias PR, Nayar S, Chen E, Villaverde N, Facey JA, Boschetti G, Giri M, Castillo-Martin M, Thin TH, Sharma Y, Chu J, Cho JH. Chuang LS, et al. Among authors: nayar s. Dis Model Mech. 2019 Aug 13;12(8):dmm037432. doi: 10.1242/dmm.037432. Dis Model Mech. 2019. PMID: 31337664 Free PMC article.
Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target.
Chen E, Chuang LS, Giri M, Villaverde N, Hsu NY, Sabic K, Joshowitz S, Gettler K, Nayar S, Chai Z, Alter IL, Chasteau CC, Korie UM, Dzedzik S, Thin TH, Jain A, Moscati A, Bongers G, Duerr RH, Silverberg MS, Brant SR, Rioux JD, Peter I, Schumm LP, Haritunians T, McGovern DP, Itan Y, Cho JH. Chen E, et al. Among authors: nayar s. Gastroenterology. 2021 Apr;160(5):1709-1724. doi: 10.1053/j.gastro.2020.12.076. Epub 2021 Jan 6. Gastroenterology. 2021. PMID: 33421512 Free PMC article.
A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease.
Nayar S, Morrison JK, Giri M, Gettler K, Chuang LS, Walker LA, Ko HM, Kenigsberg E, Kugathasan S, Merad M, Chu J, Cho JH. Nayar S, et al. Nature. 2021 May;593(7858):275-281. doi: 10.1038/s41586-021-03484-5. Epub 2021 Mar 31. Nature. 2021. PMID: 33789339 Free PMC article.
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.
Martin JC, Chang C, Boschetti G, Ungaro R, Giri M, Grout JA, Gettler K, Chuang LS, Nayar S, Greenstein AJ, Dubinsky M, Walker L, Leader A, Fine JS, Whitehurst CE, Mbow ML, Kugathasan S, Denson LA, Hyams JS, Friedman JR, Desai PT, Ko HM, Laface I, Akturk G, Schadt EE, Salmon H, Gnjatic S, Rahman AH, Merad M, Cho JH, Kenigsberg E. Martin JC, et al. Among authors: nayar s. Cell. 2019 Sep 5;178(6):1493-1508.e20. doi: 10.1016/j.cell.2019.08.008. Epub 2019 Aug 29. Cell. 2019. PMID: 31474370 Free PMC article.
A Role for CXCR3 Ligands as Biomarkers of Post-Operative Crohn's Disease Recurrence.
Walshe M, Nayeri S, Ji J, Hernandez-Rocha C, Sabic K, Hu L, Giri M, Nayar S, Brant S, McGovern DPB, Rioux JD, Duerr RH, Cho JH, Schumm PL, Lazarev M, Silverberg MS. Walshe M, et al. Among authors: nayar s. J Crohns Colitis. 2022 Jul 14;16(6):900-910. doi: 10.1093/ecco-jcc/jjab186. J Crohns Colitis. 2022. PMID: 34698823 Free PMC article.
trappc11 is required for protein glycosylation in zebrafish and humans.
DeRossi C, Vacaru A, Rafiq R, Cinaroglu A, Imrie D, Nayar S, Baryshnikova A, Milev MP, Stanga D, Kadakia D, Gao N, Chu J, Freeze HH, Lehrman MA, Sacher M, Sadler KC. DeRossi C, et al. Among authors: nayar s. Mol Biol Cell. 2016 Apr 15;27(8):1220-34. doi: 10.1091/mbc.E15-08-0557. Epub 2016 Feb 24. Mol Biol Cell. 2016. PMID: 26912795 Free PMC article.
379 results