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Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection.
Oh CK, Nakamura T, Beutler N, Zhang X, Piña-Crespo J, Talantova M, Ghatak S, Trudler D, Carnevale LN, McKercher SR, Bakowski MA, Diedrich JK, Roberts AJ, Woods AK, Chi V, Gupta AK, Rosenfeld MA, Kearns FL, Casalino L, Shaabani N, Liu H, Wilson IA, Amaro RE, Burton DR, Yates JR 3rd, Becker C, Rogers TF, Chatterjee AK, Lipton SA. Oh CK, et al. Among authors: liu h. Nat Chem Biol. 2023 Mar;19(3):275-283. doi: 10.1038/s41589-022-01149-6. Epub 2022 Sep 29. Nat Chem Biol. 2023. PMID: 36175661 Free PMC article.
Structural basis of a public antibody response to SARS-CoV-2.
Yuan M, Liu H, Wu NC, Lee CD, Zhu X, Zhao F, Huang D, Yu W, Hua Y, Tien H, Rogers TF, Landais E, Sok D, Jardine JG, Burton DR, Wilson IA. Yuan M, et al. Among authors: liu h. bioRxiv [Preprint]. 2020 Jun 9:2020.06.08.141267. doi: 10.1101/2020.06.08.141267. bioRxiv. 2020. Update in: Science. 2020 Aug 28;369(6507):1119-1123. doi: 10.1126/science.abd2321 PMID: 32577642 Free PMC article. Updated. Preprint.
Structural basis of a shared antibody response to SARS-CoV-2.
Yuan M, Liu H, Wu NC, Lee CD, Zhu X, Zhao F, Huang D, Yu W, Hua Y, Tien H, Rogers TF, Landais E, Sok D, Jardine JG, Burton DR, Wilson IA. Yuan M, et al. Among authors: liu h. Science. 2020 Aug 28;369(6507):1119-1123. doi: 10.1126/science.abd2321. Epub 2020 Jul 13. Science. 2020. PMID: 32661058 Free PMC article.
An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain.
Wu NC, Yuan M, Liu H, Lee CD, Zhu X, Bangaru S, Torres JL, Caniels TG, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Wu NC, et al. Among authors: liu h. bioRxiv [Preprint]. 2020 Jul 27:2020.07.26.222232. doi: 10.1101/2020.07.26.222232. bioRxiv. 2020. Update in: Cell Rep. 2020 Oct 20;33(3):108274. doi: 10.1016/j.celrep.2020.108274 PMID: 32743580 Free PMC article. Updated. Preprint.
Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity.
Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Liu H, et al. bioRxiv [Preprint]. 2020 Aug 3:2020.08.02.233536. doi: 10.1101/2020.08.02.233536. bioRxiv. 2020. Update in: Immunity. 2020 Dec 15;53(6):1272-1280.e5. doi: 10.1016/j.immuni.2020.10.023 PMID: 32793906 Free PMC article. Updated. Preprint.
A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
Kreye J, Reincke SM, Kornau HC, Sánchez-Sendin E, Max Corman V, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Höltje M, Dietert K, Stöffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Prüss H. Kreye J, et al. Among authors: liu h. bioRxiv [Preprint]. 2020 Aug 16:2020.08.15.252320. doi: 10.1101/2020.08.15.252320. bioRxiv. 2020. Update in: Cell. 2020 Nov 12;183(4):1058-1069.e19. doi: 10.1016/j.cell.2020.09.049 PMID: 32817952 Free PMC article. Updated. Preprint.
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Kreye J, Reincke SM, Kornau HC, Sánchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Höltje M, Dietert K, Stöffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Müller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Prüss H. Kreye J, et al. Among authors: liu h. Cell. 2020 Nov 12;183(4):1058-1069.e19. doi: 10.1016/j.cell.2020.09.049. Epub 2020 Sep 23. Cell. 2020. PMID: 33058755 Free PMC article.
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