Reddy ST - Search Results

1

High-throughput T cell receptor engineering by functional screening identifies candidates with enhanced potency and specificity.

Vazquez-Lombardi R, Jung JS, Schlatter FS, Mei A, Mantuano NR, Bieberich F, Hong KL, Kucharczyk J, Kapetanovic E, Aznauryan E, Weber CR, Zippelius A, Läubli H, Reddy ST. Vazquez-Lombardi R, et al. Among authors: reddy st. Immunity. 2022 Oct 11;55(10):1953-1966.e10. doi: 10.1016/j.immuni.2022.09.004. Epub 2022 Sep 28. Immunity. 2022. PMID: 36174557 Free article.

2

Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.

Müller P, Kreuzaler M, Khan T, Thommen DS, Martin K, Glatz K, Savic S, Harbeck N, Nitz U, Gluz O, von Bergwelt-Baildon M, Kreipe H, Reddy S, Christgen M, Zippelius A. Müller P, et al. Sci Transl Med. 2015 Nov 25;7(315):315ra188. doi: 10.1126/scitranslmed.aac4925. Sci Transl Med. 2015. PMID: 26606967

3

Systems Analysis Reveals High Genetic and Antigen-Driven Predetermination of Antibody Repertoires throughout B Cell Development.

Greiff V, Menzel U, Miho E, Weber C, Riedel R, Cook S, Valai A, Lopes T, Radbruch A, Winkler TH, Reddy ST. Greiff V, et al. Among authors: reddy st. Cell Rep. 2017 May 16;19(7):1467-1478. doi: 10.1016/j.celrep.2017.04.054. Cell Rep. 2017. PMID: 28514665 Free article.

4

Learning the High-Dimensional Immunogenomic Features That Predict Public and Private Antibody Repertoires.

Greiff V, Weber CR, Palme J, Bodenhofer U, Miho E, Menzel U, Reddy ST. Greiff V, et al. Among authors: reddy st. J Immunol. 2017 Oct 15;199(8):2985-2997. doi: 10.4049/jimmunol.1700594. Epub 2017 Sep 18. J Immunol. 2017. PMID: 28924003

5

Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires.

Miho E, Yermanos A, Weber CR, Berger CT, Reddy ST, Greiff V. Miho E, et al. Among authors: reddy st. Front Immunol. 2018 Feb 21;9:224. doi: 10.3389/fimmu.2018.00224. eCollection 2018. Front Immunol. 2018. PMID: 29515569 Free PMC article. Review.

6

High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis.

Mason DM, Weber CR, Parola C, Meng SM, Greiff V, Kelton WJ, Reddy ST. Mason DM, et al. Among authors: reddy st. Nucleic Acids Res. 2018 Aug 21;46(14):7436-7449. doi: 10.1093/nar/gky550. Nucleic Acids Res. 2018. PMID: 29931269 Free PMC article.

7

A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer.

D'Amico L, Menzel U, Prummer M, Müller P, Buchi M, Kashyap A, Haessler U, Yermanos A, Gébleux R, Briendl M, Hell T, Wolter FI, Beerli RR, Truxova I, Radek Š, Vlajnic T, Grawunder U, Reddy S, Zippelius A. D'Amico L, et al. J Immunother Cancer. 2019 Jan 21;7(1):16. doi: 10.1186/s40425-018-0464-1. J Immunother Cancer. 2019. PMID: 30665463 Free PMC article.

8

immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking.

Weber CR, Akbar R, Yermanos A, Pavlović M, Snapkov I, Sandve GK, Reddy ST, Greiff V. Weber CR, et al. Among authors: reddy st. Bioinformatics. 2020 Jun 1;36(11):3594-3596. doi: 10.1093/bioinformatics/btaa158. Bioinformatics. 2020. PMID: 32154832 Free PMC article.

9

A Functional Screening Strategy for Engineering Chimeric Antigen Receptors with Reduced On-Target, Off-Tumor Activation.

Di Roberto RB, Castellanos-Rueda R, Frey S, Egli D, Vazquez-Lombardi R, Kapetanovic E, Kucharczyk J, Reddy ST. Di Roberto RB, et al. Among authors: reddy st. Mol Ther. 2020 Dec 2;28(12):2564-2576. doi: 10.1016/j.ymthe.2020.08.003. Epub 2020 Aug 8. Mol Ther. 2020. PMID: 32827460 Free PMC article.

10

Leveraging Single-Cell Sequencing for Chimeric Antigen Receptor T Cell Therapies.

Castellanos-Rueda R, Di Roberto RB, Schlatter FS, Reddy ST. Castellanos-Rueda R, et al. Among authors: reddy st. Trends Biotechnol. 2021 Dec;39(12):1308-1320. doi: 10.1016/j.tibtech.2021.03.005. Epub 2021 Apr 5. Trends Biotechnol. 2021. PMID: 33832782 Review.

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