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Actin maturation requires the ACTMAP/C19orf54 protease.
Haahr P, Galli RA, van den Hengel LG, Bleijerveld OB, Kazokaitė-Adomaitienė J, Song JY, Kroese LJ, Krimpenfort P, Baltissen MP, Vermeulen M, Ottenheijm CAC, Brummelkamp TR. Haahr P, et al. Among authors: song jy. Science. 2022 Sep 30;377(6614):1533-1537. doi: 10.1126/science.abq5082. Epub 2022 Sep 29. Science. 2022. PMID: 36173861
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
Loregger A, Raaben M, Nieuwenhuis J, Tan JME, Jae LT, van den Hengel LG, Hendrix S, van den Berg M, Scheij S, Song JY, Huijbers IJ, Kroese LJ, Ottenhoff R, van Weeghel M, van de Sluis B, Brummelkamp T, Zelcer N. Loregger A, et al. Among authors: song jy. Nat Commun. 2020 Feb 28;11(1):1128. doi: 10.1038/s41467-020-14811-1. Nat Commun. 2020. PMID: 32111832 Free PMC article.
Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice.
Badhai J, Pandey GK, Song JY, Krijgsman O, Bhaskaran R, Chandrasekaran G, Kwon MC, Bombardelli L, Monkhorst K, Grasso C, Zevenhoven J, van der Vliet J, Cozijnsen M, Krimpenfort P, Peeper D, van Lohuizen M, Berns A. Badhai J, et al. Among authors: song jy. J Exp Med. 2020 Jun 1;217(6):e20191257. doi: 10.1084/jem.20191257. J Exp Med. 2020. PMID: 32271879 Free PMC article.
Posttranslational modification of microtubules by the MATCAP detyrosinase.
Landskron L, Bak J, Adamopoulos A, Kaplani K, Moraiti M, van den Hengel LG, Song JY, Bleijerveld OB, Nieuwenhuis J, Heidebrecht T, Henneman L, Moutin MJ, Barisic M, Taraviras S, Perrakis A, Brummelkamp TR. Landskron L, et al. Among authors: song jy. Science. 2022 May 20;376(6595):eabn6020. doi: 10.1126/science.abn6020. Epub 2022 May 20. Science. 2022. PMID: 35482892
Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development.
Gan C, Wang J, Wang Y, Martínez-Chávez A, Hillebrand M, de Vries N, Beukers J, Lebre MC, Wagenaar E, Rosing H, Klarenbeek S, Bleijerveld OB, Song JY, Altelaar M, Beijnen JH, Schinkel AH. Gan C, et al. Among authors: song jy. Biomed Pharmacother. 2023 Aug;164:114956. doi: 10.1016/j.biopha.2023.114956. Epub 2023 May 31. Biomed Pharmacother. 2023. PMID: 37267638 Free article.
Identification of an alternative triglyceride biosynthesis pathway.
McLelland GL, Lopez-Osias M, Verzijl CRC, Ellenbroek BD, Oliveira RA, Boon NJ, Dekker M, van den Hengel LG, Ali R, Janssen H, Song JY, Krimpenfort P, van Zutphen T, Jonker JW, Brummelkamp TR. McLelland GL, et al. Among authors: song jy. Nature. 2023 Sep;621(7977):171-178. doi: 10.1038/s41586-023-06497-4. Epub 2023 Aug 30. Nature. 2023. PMID: 37648867 Free PMC article.
1,870 results