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Page 1
Actin maturation requires the ACTMAP/C19orf54 protease.
Haahr P, Galli RA, van den Hengel LG, Bleijerveld OB, Kazokaitė-Adomaitienė J, Song JY, Kroese LJ, Krimpenfort P, Baltissen MP, Vermeulen M, Ottenheijm CAC, Brummelkamp TR. Haahr P, et al. Science. 2022 Sep 30;377(6614):1533-1537. doi: 10.1126/science.abq5082. Epub 2022 Sep 29. Science. 2022. PMID: 36173861
ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle.
Nordgaard C, Vind AC, Stonadge A, Kjøbsted R, Snieckute G, Antas P, Blasius M, Reinert MS, Del Val AM, Bekker-Jensen DB, Haahr P, Miroshnikova YA, Mazouzi A, Falk S, Perrier-Groult E, Tiedje C, Li X, Jakobsen JR, Jørgensen NO, Wojtaszewski JF, Mallein-Gerin F, Andersen JL, Pennisi CP, Clemmensen C, Kassem M, Jafari A, Brummelkamp T, Li VS, Wickström SA, Olsen JV, Blanco G, Bekker-Jensen S. Nordgaard C, et al. Among authors: haahr p. EMBO J. 2022 Sep 1;41(17):e111650. doi: 10.15252/embj.2022111650. Epub 2022 Jul 28. EMBO J. 2022. PMID: 35899396 Free PMC article.
Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation.
Liu JCY, Ackermann L, Hoffmann S, Gál Z, Hendriks IA, Jain C, Morlot L, Tatham MH, McLelland GL, Hay RT, Nielsen ML, Brummelkamp T, Haahr P, Mailand N. Liu JCY, et al. Among authors: haahr p. Nat Struct Mol Biol. 2024 Sep;31(9):1355-1367. doi: 10.1038/s41594-024-01294-7. Epub 2024 Apr 22. Nat Struct Mol Biol. 2024. PMID: 38649616 Free PMC article.
DNA damage induces p53-independent apoptosis through ribosome stalling.
Boon NJ, Oliveira RA, Körner PR, Kochavi A, Mertens S, Malka Y, Voogd R, van der Horst SEM, Huismans MA, Smabers LP, Draper JM, Wessels LFA, Haahr P, Roodhart JML, Schumacher TNM, Snippert HJ, Agami R, Brummelkamp TR. Boon NJ, et al. Among authors: haahr p. Science. 2024 May 17;384(6697):785-792. doi: 10.1126/science.adh7950. Epub 2024 May 16. Science. 2024. PMID: 38753784
Activation of the ATR kinase by the RPA-binding protein ETAA1.
Haahr P, Hoffmann S, Tollenaere MA, Ho T, Toledo LI, Mann M, Bekker-Jensen S, Räschle M, Mailand N. Haahr P, et al. Nat Cell Biol. 2016 Nov;18(11):1196-1207. doi: 10.1038/ncb3422. Epub 2016 Oct 10. Nat Cell Biol. 2016. PMID: 27723717
Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway.
Liu JCY, Kühbacher U, Larsen NB, Borgermann N, Garvanska DH, Hendriks IA, Ackermann L, Haahr P, Gallina I, Guérillon C, Branigan E, Hay RT, Azuma Y, Nielsen ML, Duxin JP, Mailand N. Liu JCY, et al. Among authors: haahr p. EMBO J. 2021 Sep 15;40(18):e107413. doi: 10.15252/embj.2020107413. Epub 2021 Aug 4. EMBO J. 2021. PMID: 34346517 Free PMC article.
55 results