Newton AC - Search Results

1

Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition.

Pilo CA, Baffi TR, Kornev AP, Kunkel MT, Malfavon M, Chen DH, Rossitto LA, Chen DX, Huang LC, Longman C, Kannan N, Raskind WH, Gonzalez DJ, Taylor SS, Gorrie G, Newton AC. Pilo CA, et al. Among authors: newton ac. Sci Signal. 2022 Sep 27;15(753):eabk1147. doi: 10.1126/scisignal.abk1147. Epub 2022 Sep 27. Sci Signal. 2022. PMID: 36166510 Free PMC article.

2

Protein kinase C. Seeing two domains.

Newton AC. Newton AC. Curr Biol. 1995 Sep 1;5(9):973-6. doi: 10.1016/s0960-9822(95)00191-6. Curr Biol. 1995. PMID: 8542286 Free article. Review.

3

Diacylglycerol's affair with protein kinase C turns 25.

Newton AC. Newton AC. Trends Pharmacol Sci. 2004 Apr;25(4):175-7. doi: 10.1016/j.tips.2004.02.010. Trends Pharmacol Sci. 2004. PMID: 15116719 Review.

4

Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter.

Kunkel MT, Ni Q, Tsien RY, Zhang J, Newton AC. Kunkel MT, et al. Among authors: newton ac. J Biol Chem. 2005 Feb 18;280(7):5581-7. doi: 10.1074/jbc.M411534200. Epub 2004 Dec 6. J Biol Chem. 2005. PMID: 15583002 Free PMC article.

5

Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling.

Gallegos LL, Kunkel MT, Newton AC. Gallegos LL, et al. Among authors: newton ac. J Biol Chem. 2006 Oct 13;281(41):30947-56. doi: 10.1074/jbc.M603741200. Epub 2006 Aug 10. J Biol Chem. 2006. PMID: 16901905 Free article.

6

A single residue in the C1 domain sensitizes novel protein kinase C isoforms to cellular diacylglycerol production.

Dries DR, Gallegos LL, Newton AC. Dries DR, et al. Among authors: newton ac. J Biol Chem. 2007 Jan 12;282(2):826-30. doi: 10.1074/jbc.C600268200. Epub 2006 Oct 27. J Biol Chem. 2007. PMID: 17071619 Free article.

7

Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter.

Kunkel MT, Toker A, Tsien RY, Newton AC. Kunkel MT, et al. Among authors: newton ac. J Biol Chem. 2007 Mar 2;282(9):6733-42. doi: 10.1074/jbc.M608086200. Epub 2006 Dec 21. J Biol Chem. 2007. PMID: 17189263 Free PMC article.

8

Spatiotemporal dynamics of lipid signaling: protein kinase C as a paradigm.

Gallegos LL, Newton AC. Gallegos LL, et al. Among authors: newton ac. IUBMB Life. 2008 Dec;60(12):782-9. doi: 10.1002/iub.122. IUBMB Life. 2008. PMID: 18720411 Free PMC article. Review.

9

The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail.

Gould CM, Kannan N, Taylor SS, Newton AC. Gould CM, et al. Among authors: newton ac. J Biol Chem. 2009 Feb 20;284(8):4921-35. doi: 10.1074/jbc.M808436200. Epub 2008 Dec 17. J Biol Chem. 2009. PMID: 19091746 Free PMC article.

10

The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity.

Kunkel MT, Garcia EL, Kajimoto T, Hall RA, Newton AC. Kunkel MT, et al. Among authors: newton ac. J Biol Chem. 2009 Sep 4;284(36):24653-61. doi: 10.1074/jbc.M109.024547. Epub 2009 Jul 6. J Biol Chem. 2009. PMID: 19581308 Free PMC article.

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