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Page 1
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition.
Pilo CA, Baffi TR, Kornev AP, Kunkel MT, Malfavon M, Chen DH, Rossitto LA, Chen DX, Huang LC, Longman C, Kannan N, Raskind WH, Gonzalez DJ, Taylor SS, Gorrie G, Newton AC. Pilo CA, et al. Among authors: gonzalez dj. Sci Signal. 2022 Sep 27;15(753):eabk1147. doi: 10.1126/scisignal.abk1147. Epub 2022 Sep 27. Sci Signal. 2022. PMID: 36166510 Free PMC article.
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.
Baffi TR, Lordén G, Wozniak JM, Feichtner A, Yeung W, Kornev AP, King CC, Del Rio JC, Limaye AJ, Bogomolovas J, Gould CM, Chen J, Kennedy EJ, Kannan N, Gonzalez DJ, Stefan E, Taylor SS, Newton AC. Baffi TR, et al. Among authors: gonzalez dj. Sci Signal. 2021 Apr 13;14(678):eabe4509. doi: 10.1126/scisignal.abe4509. Sci Signal. 2021. PMID: 33850054 Free PMC article.
Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity.
Mills RH, Dulai PS, Vázquez-Baeza Y, Sauceda C, Daniel N, Gerner RR, Batachari LE, Malfavon M, Zhu Q, Weldon K, Humphrey G, Carrillo-Terrazas M, Goldasich LD, Bryant M, Raffatellu M, Quinn RA, Gewirtz AT, Chassaing B, Chu H, Sandborn WJ, Dorrestein PC, Knight R, Gonzalez DJ. Mills RH, et al. Among authors: gonzalez dj. Nat Microbiol. 2022 Feb;7(2):262-276. doi: 10.1038/s41564-021-01050-3. Epub 2022 Jan 27. Nat Microbiol. 2022. PMID: 35087228 Free PMC article.
The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients.
Gonzalez CG, Mills RH, Kordahi MC, Carrillo-Terrazas M, Secaira-Morocho H, Widjaja CE, Tsai MS, Mittal Y, Yee BA, Vargas F, Weldon K, Gauglitz JM, Delaroque C, Sauceda C, Rossitto LA, Ackermann G, Humphrey G, Swafford AD, Siegel CA, Buckey JC Jr, Raffals LE, Sadler C, Lindholm P, Fisch KM, Valaseck M, Suriawinata A, Yeo GW, Ghosh P, Chang JT, Chu H, Dorrestein P, Zhu Q, Chassaing B, Knight R, Gonzalez DJ, Dulai PS. Gonzalez CG, et al. Among authors: gonzalez dj. Cell Mol Gastroenterol Hepatol. 2022;14(1):35-53. doi: 10.1016/j.jcmgh.2022.03.008. Epub 2022 Apr 1. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35378331 Free PMC article.
Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes.
Russell BJ, Brown SD, Siguenza N, Mai I, Saran AR, Lingaraju A, Maissy ES, Dantas Machado AC, Pinto AFM, Sanchez C, Rossitto LA, Miyamoto Y, Richter RA, Ho SB, Eckmann L, Hasty J, Gonzalez DJ, Saghatelian A, Knight R, Zarrinpar A. Russell BJ, et al. Among authors: gonzalez dj. Cell. 2022 Aug 18;185(17):3263-3277.e15. doi: 10.1016/j.cell.2022.06.050. Epub 2022 Aug 4. Cell. 2022. PMID: 35931082 Free PMC article.
Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia.
Elsaid K, Merriman TR, Rossitto LA, Liu-Bryan R, Karsh J, Phipps-Green A, Jay GD, Elsayed S, Qadri M, Miner M, Cadzow M, Dambruoso TJ, Schmidt TA, Dalbeth N, Chhana A, Höglund J, Ghassemian M, Campeau A, Maltez N, Karlsson NG, Gonzalez DJ, Terkeltaub R. Elsaid K, et al. Among authors: gonzalez dj. Arthritis Rheumatol. 2023 May;75(5):794-805. doi: 10.1002/art.42413. Epub 2023 Mar 10. Arthritis Rheumatol. 2023. PMID: 36457235 Free PMC article.
A bacterial sialidase mediates early-life colonization by a pioneering gut commensal.
Buzun E, Hsu CY, Sejane K, Oles RE, Vasquez Ayala A, Loomis LR, Zhao J, Rossitto LA, McGrosso DM, Gonzalez DJ, Bode L, Chu H. Buzun E, et al. Among authors: gonzalez dj. Cell Host Microbe. 2024 Feb 14;32(2):181-190.e9. doi: 10.1016/j.chom.2023.12.014. Epub 2024 Jan 15. Cell Host Microbe. 2024. PMID: 38228143
160 results