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Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus.
Leibler C, John S, Elsner RA, Thomas KB, Smita S, Joachim S, Levack RC, Callahan DJ, Gordon RA, Bastacky S, Fukui R, Miyake K, Gingras S, Nickerson KM, Shlomchik MJ. Leibler C, et al. Among authors: bastacky s. Nat Immunol. 2022 Oct;23(10):1457-1469. doi: 10.1038/s41590-022-01310-2. Epub 2022 Sep 23. Nat Immunol. 2022. PMID: 36151396 Free PMC article.
B cell-intrinsic TLR9 expression is protective in murine lupus.
Tilstra JS, John S, Gordon RA, Leibler C, Kashgarian M, Bastacky S, Nickerson KM, Shlomchik MJ. Tilstra JS, et al. Among authors: bastacky s. J Clin Invest. 2020 Jun 1;130(6):3172-3187. doi: 10.1172/JCI132328. J Clin Invest. 2020. PMID: 32191633 Free PMC article.
Murine lupus is neutrophil elastase-independent in the MRL.Faslpr model.
Gordon RA, Tilstra JS, Marinov A, Nickerson KM, Bastacky SI, Shlomchik MJ. Gordon RA, et al. Among authors: bastacky si. PLoS One. 2020 Apr 3;15(4):e0226396. doi: 10.1371/journal.pone.0226396. eCollection 2020. PLoS One. 2020. PMID: 32243431 Free PMC article.
Lupus and proliferative nephritis are PAD4 independent in murine models.
Gordon RA, Herter JM, Rosetti F, Campbell AM, Nishi H, Kashgarian M, Bastacky SI, Marinov A, Nickerson KM, Mayadas TN, Shlomchik MJ. Gordon RA, et al. JCI Insight. 2017 May 18;2(10):e92926. doi: 10.1172/jci.insight.92926. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515361 Free PMC article.
144 results