van Ham WB - Search Results

1

Uremic toxins in chronic kidney disease highlight a fundamental gap in understanding their detrimental effects on cardiac electrophysiology and arrhythmogenesis.

van Ham WB, Cornelissen CM, van Veen TAB. van Ham WB, et al. Acta Physiol (Oxf). 2022 Nov;236(3):e13888. doi: 10.1111/apha.13888. Epub 2022 Oct 1. Acta Physiol (Oxf). 2022. PMID: 36148604 Free PMC article. Review.

2

Clinical Phenotypes of Heart Failure With Preserved Ejection Fraction to Select Preclinical Animal Models.

van Ham WB, Kessler EL, Oerlemans MIFJ, Handoko ML, Sluijter JPG, van Veen TAB, den Ruijter HM, de Jager SCA. van Ham WB, et al. JACC Basic Transl Sci. 2022 May 25;7(8):844-857. doi: 10.1016/j.jacbts.2021.12.009. eCollection 2022 Aug. JACC Basic Transl Sci. 2022. PMID: 36061340 Free PMC article. Review.

3

Quantitative Analysis of the Cytoskeleton's Role in Inward Rectifier K _IR 2.1 Forward and Backward Trafficking.

Li E, Loen V, van Ham WB, Kool W, van der Heyden MAG, Takanari H. Li E, et al. Among authors: van ham wb. Front Physiol. 2022 Jan 25;12:812572. doi: 10.3389/fphys.2021.812572. eCollection 2021. Front Physiol. 2022. PMID: 35145427 Free PMC article.

4

LUF7244, an allosteric modulator/activator of K_v 11.1 channels, counteracts dofetilide-induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model.

Qile M, Beekman HDM, Sprenkeler DJ, Houtman MJC, van Ham WB, Stary-Weinzinger A, Beyl S, Hering S, van den Berg DJ, de Lange ECM, Heitman LH, IJzerman AP, Vos MA, van der Heyden MAG. Qile M, et al. Among authors: van den berg dj, van ham wb, van der heyden mag. Br J Pharmacol. 2019 Oct;176(19):3871-3885. doi: 10.1111/bph.14798. Epub 2019 Aug 30. Br J Pharmacol. 2019. PMID: 31339551 Free PMC article.

5

LUF7244 plus Dofetilide Rescues Aberrant K_v11.1 Trafficking and Produces Functional I_Kv11.1.

Qile M, Ji Y, Golden TD, Houtman MJC, Romunde F, Fransen D, van Ham WB, IJzerman AP, January CT, Heitman LH, Stary-Weinzinger A, Delisle BP, van der Heyden MAG. Qile M, et al. Among authors: van ham wb, van der heyden mag. Mol Pharmacol. 2020 Jun;97(6):355-364. doi: 10.1124/mol.119.118190. Epub 2020 Apr 2. Mol Pharmacol. 2020. PMID: 32241959

6

Histidine at position 462 determines the low quinine sensitivity of ether-à-go-go channel superfamily member K_v 12.1.

Dierich M, van Ham WB, Stary-Weinzinger A, Leitner MG. Dierich M, et al. Among authors: van ham wb. Br J Pharmacol. 2019 Aug;176(15):2708-2723. doi: 10.1111/bph.14693. Epub 2019 Jun 17. Br J Pharmacol. 2019. PMID: 31032878 Free PMC article.

7

An hiPSC-CM approach for electrophysiological phenotyping of a patient-specific case of short-coupled TdP.

van Ham WB, Meijboom EEM, Ligtermoet ML, Monshouwer-Kloots J, Riele ASJMT, Asselbergs FW, van Rooij E, Bourfiss M, van Veen TAB. van Ham WB, et al. Stem Cell Res Ther. 2024 Dec 18;15(1):470. doi: 10.1186/s13287-024-04074-8. Stem Cell Res Ther. 2024. PMID: 39695883 Free PMC article.

8

Development of new K_ir2.1 channel openers from propafenone analogues.

Li E, Boujeddaine N, Houtman MJC, Maas RGC, Sluijter JPG, Ecker GF, Stary-Weinzinger A, van Ham WB, van der Heyden MAG. Li E, et al. Among authors: van ham wb. Br J Pharmacol. 2025 Feb;182(3):633-650. doi: 10.1111/bph.17377. Epub 2024 Oct 17. Br J Pharmacol. 2025. PMID: 39419581

9

Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart.

Gladka MM, Kohela A, de Leeuw AE, Molenaar B, Versteeg D, Kooijman L, van Geldorp M, van Ham WB, Caliandro R, Haigh JJ, van Veen TAB, van Rooij E. Gladka MM, et al. Among authors: van ham wb. Cardiovasc Res. 2024 Dec 4;120(15):1869-1883. doi: 10.1093/cvr/cvae163. Cardiovasc Res. 2024. PMID: 39308239 Free PMC article.

10

Maturation and Function of the Intercalated Disc: Report of Two Pediatric Cases Focusing on Cardiac Development and Myocardial Hyperplasia.

van Ham WB, Meijboom EEM, Ligtermoet ML, Nikkels PGJ, van Veen TAB. van Ham WB, et al. J Cardiovasc Dev Dis. 2023 Aug 19;10(8):354. doi: 10.3390/jcdd10080354. J Cardiovasc Dev Dis. 2023. PMID: 37623366 Free PMC article.

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