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Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders.
El Andari J, Renaud-Gabardos E, Tulalamba W, Weinmann J, Mangin L, Pham QH, Hille S, Bennett A, Attebi E, Bourges E, Leborgne C, Guerchet N, Fakhiri J, Krämer C, Wiedtke E, McKenna R, Guianvarc'h L, Toueille M, Ronzitti G, Hebben M, Mingozzi F, VandenDriessche T, Agbandje-McKenna M, Müller OJ, Chuah MK, Buj-Bello A, Grimm D. El Andari J, et al. Among authors: fakhiri j. Sci Adv. 2022 Sep 23;8(38):eabn4704. doi: 10.1126/sciadv.abn4704. Epub 2022 Sep 21. Sci Adv. 2022. PMID: 36129972 Free PMC article.
Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening.
Börner K, Kienle E, Huang LY, Weinmann J, Sacher A, Bayer P, Stüllein C, Fakhiri J, Zimmermann L, Westhaus A, Beneke J, Beil N, Wiedtke E, Schmelas C, Miltner D, Rau A, Erfle H, Kräusslich HG, Müller M, Agbandje-McKenna M, Grimm D. Börner K, et al. Among authors: fakhiri j. Mol Ther. 2020 Apr 8;28(4):1016-1032. doi: 10.1016/j.ymthe.2020.02.009. Epub 2020 Feb 13. Mol Ther. 2020. PMID: 32105604 Free PMC article.
Novel Chimeric Gene Therapy Vectors Based on Adeno-Associated Virus and Four Different Mammalian Bocaviruses.
Fakhiri J, Schneider MA, Puschhof J, Stanifer M, Schildgen V, Holderbach S, Voss Y, El Andari J, Schildgen O, Boulant S, Meister M, Clevers H, Yan Z, Qiu J, Grimm D. Fakhiri J, et al. Mol Ther Methods Clin Dev. 2019 Jan 18;12:202-222. doi: 10.1016/j.omtm.2019.01.003. eCollection 2019 Mar 15. Mol Ther Methods Clin Dev. 2019. PMID: 30766894 Free PMC article.
Characterization of the GBoV1 Capsid and Its Antibody Interactions.
Yu JC, Mietzsch M, Singh A, Jimenez Ybargollin A, Kailasan S, Chipman P, Bhattacharya N, Fakhiri J, Grimm D, Kapoor A, Kučinskaitė-Kodzė I, Žvirblienė A, Söderlund-Venermo M, McKenna R, Agbandje-McKenna M. Yu JC, et al. Among authors: fakhiri j. Viruses. 2021 Feb 20;13(2):330. doi: 10.3390/v13020330. Viruses. 2021. PMID: 33672786 Free PMC article.
15 results