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Page 1
Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality.
Sano S, Horitani K, Ogawa H, Halvardson J, Chavkin NW, Wang Y, Sano M, Mattisson J, Hata A, Danielsson M, Miura-Yura E, Zaghlool A, Evans MA, Fall T, De Hoyos HN, Sundström J, Yura Y, Kour A, Arai Y, Thel MC, Arai Y, Mychaleckyj JC, Hirschi KK, Forsberg LA, Walsh K. Sano S, et al. Among authors: thel mc. Science. 2022 Jul 15;377(6603):292-297. doi: 10.1126/science.abn3100. Epub 2022 Jul 14. Science. 2022. PMID: 35857592 Free PMC article.
Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction.
Cochran JD, Yura Y, Thel MC, Doviak H, Polizio AH, Arai Y, Arai Y, Horitani K, Park E, Chavkin NW, Kour A, Sano S, Mahajan N, Evans M, Huba M, Naya NM, Sun H, Ban YH, Hirschi KK, Toldo S, Abbate A, Druley TE, Ruberg FL, Maurer MS, Ezekowitz JA, Dyck JRB, Walsh K. Cochran JD, et al. Among authors: thel mc. Circulation. 2023 Oct 10;148(15):1165-1178. doi: 10.1161/CIRCULATIONAHA.123.064170. Epub 2023 Sep 8. Circulation. 2023. PMID: 37681311 Free PMC article.
Mosaic Loss of the Y Chromosome Is Enriched in Patients With Wild-Type Transthyretin Cardiac Amyloidosis and Associated With Increased Mortality.
Thel MC, Cochran JD, Teruya S, Hayashi O, Xie CR, Srinivasan AR, Chavkin NW, Arai Y, Sano S, Mirabal Santos A, De Los Santos J, Fine D, Sabogal N, Ullah I, Helmke S, Rodriguez C, Prokaeva T, Foster RH, Spencer BH, Izumiya Y, Maurer MS, Walsh K, Ruberg FL. Thel MC, et al. Circ Heart Fail. 2024 Aug;17(8):e011681. doi: 10.1161/CIRCHEARTFAILURE.124.011681. Epub 2024 Jun 10. Circ Heart Fail. 2024. PMID: 38853760 No abstract available.
Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure.
Horitani K, Chavkin NW, Arai Y, Wang Y, Ogawa H, Yura Y, Evans MA, Cochran JD, Thel MC, Polizio AH, Sano M, Miura-Yura E, Arai Y, Doviak H, Arnold AP, Gelfand BD, Hirschi KK, Sano S, Walsh K. Horitani K, et al. Among authors: thel mc. Nat Cardiovasc Res. 2024 Mar;3(3):343-355. doi: 10.1038/s44161-024-00441-z. Epub 2024 Mar 8. Nat Cardiovasc Res. 2024. PMID: 39183958 Free PMC article.
19 results