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A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors.
Awada G, Schwarze JK, Tijtgat J, Fasolino G, Kruse V, Neyns B. Awada G, et al. Among authors: kruse v. Melanoma Res. 2022 Jun 1;32(3):183-191. doi: 10.1097/CMR.0000000000000821. Epub 2022 Mar 29. Melanoma Res. 2022. PMID: 35377866 Clinical Trial.
Checkpoint Inhibitors in Combination With Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors: The CHEERS Phase 2 Randomized Clinical Trial.
Spaas M, Sundahl N, Kruse V, Rottey S, De Maeseneer D, Duprez F, Lievens Y, Surmont V, Brochez L, Reynders D, Danckaert W, Goetghebeur E, Van den Begin R, Van Gestel D, Renard V, Dirix P, Ost P. Spaas M, et al. Among authors: kruse v. JAMA Oncol. 2023 Sep 1;9(9):1205-1213. doi: 10.1001/jamaoncol.2023.2132. JAMA Oncol. 2023. PMID: 37410476 Free PMC article. Clinical Trial.
Mental Health and Quality of Life among Patients with Cancer during the SARS-CoV-2 Pandemic: Results from the Longitudinal ONCOVID Survey Study.
De Jaeghere EA, Kanervo H, Colman R, Schrauwen W, West P, Vandemaele N, De Pauw A, Jacobs C, Hilderson I, Saerens M, Sundahl N, Vandecasteele K, Naert E, Lapeire L, Kruse V, Rottey S, Lemmens G, Denys HG. De Jaeghere EA, et al. Among authors: kruse v. Cancers (Basel). 2022 Feb 21;14(4):1093. doi: 10.3390/cancers14041093. Cancers (Basel). 2022. PMID: 35205838 Free PMC article.
Phase 2 Trial of Nivolumab Combined With Stereotactic Body Radiation Therapy in Patients With Metastatic or Locally Advanced Inoperable Melanoma.
Sundahl N, Seremet T, Van Dorpe J, Neyns B, Ferdinande L, Meireson A, Brochez L, Kruse V, Ost P. Sundahl N, et al. Among authors: kruse v. Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):828-835. doi: 10.1016/j.ijrobp.2019.03.041. Epub 2019 Apr 3. Int J Radiat Oncol Biol Phys. 2019. PMID: 30951807 Clinical Trial.
A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases.
Jansen Y, Kruse V, Corthals J, Schats K, van Dam PJ, Seremet T, Heirman C, Brochez L, Kockx M, Thielemans K, Neyns B. Jansen Y, et al. Among authors: kruse v. Cancer Immunol Immunother. 2020 Dec;69(12):2589-2598. doi: 10.1007/s00262-020-02618-4. Epub 2020 Jun 26. Cancer Immunol Immunother. 2020. PMID: 32591862 Free PMC article. Clinical Trial.
89 results