Shao R - Search Results

1

An EGFR/HER2-targeted conjugate sensitizes gemcitabine-sensitive and resistant pancreatic cancer through different SMAD4-mediated mechanisms.

Yao H, Song W, Cao R, Ye C, Zhang L, Chen H, Wang J, Shi Y, Li R, Li Y, Liu X, Zhou X, Shao R, Li L. Yao H, et al. Among authors: shao r. Nat Commun. 2022 Sep 20;13(1):5506. doi: 10.1038/s41467-022-33037-x. Nat Commun. 2022. PMID: 36127339 Free PMC article.

2

The blockage of Ras/ERK pathway augments the sensitivity of SphK1 inhibitor SKI II in human hepatoma HepG2 cells.

Zhang C, He H, Zhang H, Yu D, Zhao W, Chen Y, Shao R. Zhang C, et al. Among authors: shao r. Biochem Biophys Res Commun. 2013 Apr 26;434(1):35-41. doi: 10.1016/j.bbrc.2013.03.070. Epub 2013 Mar 29. Biochem Biophys Res Commun. 2013. PMID: 23545258

3

The dual topoisomerase inhibitor A35 preferentially and specially targets topoisomerase 2α by enhancing pre-strand and post-strand cleavage and inhibiting DNA religation.

Zhao W, Jiang G, Bi C, Li Y, Liu J, Ye C, He H, Li L, Song D, Shao R. Zhao W, et al. Among authors: shao r. Oncotarget. 2015 Nov 10;6(35):37871-94. doi: 10.18632/oncotarget.5680. Oncotarget. 2015. PMID: 26462155 Free PMC article.

4

Site-specific PEGylation of lidamycin and its antitumor activity.

Li L, Shang B, Hu L, Shao R, Zhen Y. Li L, et al. Among authors: shao r. Acta Pharm Sin B. 2015 May;5(3):264-9. doi: 10.1016/j.apsb.2015.03.006. Epub 2015 Apr 22. Acta Pharm Sin B. 2015. PMID: 26579455 Free PMC article.

5

Synthesis and biological evaluation of 12-N-p-chlorobenzyl sophoridinol derivatives as a novel family of anticancer agents.

Bi C, Ye C, Li Y, Zhao W, Shao R, Song D. Bi C, et al. Among authors: shao r. Acta Pharm Sin B. 2016 May;6(3):222-8. doi: 10.1016/j.apsb.2016.03.004. Epub 2016 Apr 14. Acta Pharm Sin B. 2016. PMID: 27175333 Free PMC article.

6

Sophoridinol derivative 05D induces tumor cells apoptosis by topoisomerase1-mediated DNA breakage.

Zhao W, Zhang C, Bi C, Ye C, Song D, Liu X, Shao R. Zhao W, et al. Among authors: shao r. Onco Targets Ther. 2016 May 11;9:2805-17. doi: 10.2147/OTT.S103671. eCollection 2016. Onco Targets Ther. 2016. PMID: 27274276 Free PMC article.

7

Synthesis, Biological Evaluation, and Autophagy Mechanism of 12N-Substituted Sophoridinamines as Novel Anticancer Agents.

Bi C, Zhang N, Yang P, Ye C, Wang Y, Fan T, Shao R, Deng H, Song D. Bi C, et al. Among authors: shao r. ACS Med Chem Lett. 2017 Jan 5;8(2):245-250. doi: 10.1021/acsmedchemlett.6b00466. eCollection 2017 Feb 9. ACS Med Chem Lett. 2017. PMID: 28197320 Free PMC article.

8

A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway.

Gong J, Zheng Y, Wang Y, Sheng W, Li Y, Liu X, Si S, Shao R, Zhen Y. Gong J, et al. Among authors: shao r. PLoS One. 2018 Feb 2;13(2):e0191984. doi: 10.1371/journal.pone.0191984. eCollection 2018. PLoS One. 2018. PMID: 29394294 Free PMC article.

9

Internal enhancement of DNA damage by a novel bispecific antibody-drug conjugate-like therapeutics via blockage of mTOR and PD-L1 signal pathways in pancreatic cancer.

Cao R, Song W, Ye C, Liu X, Li L, Li Y, Yao H, Zhou X, Li L, Shao R. Cao R, et al. Among authors: shao r. Cancer Med. 2019 Feb;8(2):643-655. doi: 10.1002/cam4.1974. Epub 2019 Jan 25. Cancer Med. 2019. PMID: 30681288 Free PMC article.

10

Linking endotypes to omics profiles in difficult-to-control asthma using the diagnostic Chinese medicine syndrome differentiation algorithm.

Song W, Zheng S, Li M, Zhang X, Cao R, Ye C, Shao R, Li G, Li J, Liu S, Li H, Li L. Song W, et al. Among authors: shao r. J Asthma. 2020 May;57(5):532-542. doi: 10.1080/02770903.2019.1590589. Epub 2019 Mar 27. J Asthma. 2020. PMID: 30915875

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